Wisecracking mercenary Deadpool battles the evil and powerful Cable and other bad guys to save a boy's life.
| Directing | David Leitch | Director |
| Writing | Paul Wernick | Screenplay |
| Writing | Rhett Reese | Screenplay |
| Writing | Fabian Nicieza | Characters |
| Writing | Rob Liefeld | Characters |
| Production | Simon Kinberg | Producer |
| Production | Stan Lee | Executive Producer |
| Production | Rhett Reese | Executive Producer |
| Production | Ryan Reynolds | Producer |
| Production | Lauren Shuler Donner | Producer |
| Production | Aditya Sood | Executive Producer |
| Production | Paul Wernick | Executive Producer |
| Crew | Bryce Branagan | Stunts |
| Crew | Steve Brown | Stunts |
| Crew | Jimmy Chhiu | Stunts |
| Crew | Lateef Crowder | Stunts |
| Crew | Wayne Dalglish | Stunt Coordinator |
| Crew | Jayson Dumenigo | Stunt Coordinator |
| Crew | Roel Failma | Stunts |
| Crew | Tim Garris | Stunts |
| Crew | Thekla Hutyra | Stunts |
| Crew | Amy Johnston | Stunts |
| Crew | Micah Karns | Stunts |
| Crew | Eric Linden | Stunts |
| Crew | Joe Ross | Utility Stunts |
| Crew | Philip J Silvera | Stunt Coordinator |
| Camera | Jonathan Sela | Director of Photography |
| Crew | Scott J. Ateah | Stunt Coordinator |
| Editing | Craig Alpert | Editor |
| Editing | Elísabet Ronaldsdóttir | Editor |
| Production | Marisol Roncali | Casting |
| Production | Mary Vernieu | Casting |
| Art | David Scheunemann | Production Design |
| Art | Roger Fires | Art Direction |
| Art | Peter Ochotta | Art Direction |
| Art | Sandy Walker | Set Decoration |
| Art | Dan Hermansen | Supervising Art Director |
| Costume & Make-Up | Kurt and Bart | Costume Design |
| Art | Kris Bergthorson | Assistant Art Director |
| Art | Glenn Woodruff | Construction Coordinator |
| Art | Dan Sissons | Property Master |
| Art | Houman Eshraghi | Set Designer |
| Art | Peter Rzazewski | Set Designer |
| Art | Beatrix Schalk | Set Designer |
| Art | Jennifer Yee | Set Designer |
| Art | Katharina Brand | Set Dresser |
| Art | Kevin Kasper | Set Dresser |
| Costume & Make-Up | Lilia Afsahi | Hairstylist |
| Costume & Make-Up | Ailsa Macmillan | Hairstylist |
| Costume & Make-Up | Jaala Leis Wanless | Hairstylist |
| Costume & Make-Up | Monica Huppert | Makeup Department Head |
| Costume & Make-Up | Howard Lau | Tattoo Designer |
| Costume & Make-Up | Lee Gren | Tattoo Designer |
| Sound | Donald D. Brown | Boom Operator |
| Sound | Allen Yang | Boom Operator |
| Sound | Allister Mann | Boom Operator |
| Sound | Sean Massey | Dialogue Editor |
| Sound | Paul Massey | Sound Re-Recording Mixer |
| Camera | Hans Bjerno | Aerial Director of Photography |
| Camera | Tommy Douglas | Camera Operator |
| Camera | Lucas Bielan | Camera Operator |
| Camera | Sasha Proctor | Camera Operator |
| Camera | Brad McGregor | Camera Operator |
| Camera | Patrick Loungway | Second Unit Director of Photography |
| Camera | Nicholas Dent | Dolly Grip |
| Crew | Patrick Weir | Drone Operator |
| Camera | Aaron Haesler | First Assistant Camera |
| Lighting | Drew Davidson | Gaffer |
| Camera | Mark Hyde | Key Grip |
| Camera | Kevin Black | Key Grip |
| Lighting | Rob Brady | Lighting Technician |
| Lighting | Christopher Hingston | Lighting Technician |
| Lighting | Jason Tidsbury | Lighting Technician |
| Lighting | Andrew Wunder | Lighting Technician |
| Lighting | T. Michael Morris | Lighting Technician |
| Lighting | Clyde Harrelson | Lighting Technician |
| Lighting | Tess Bukowsky | Lighting Technician |
| Lighting | Keith Woods | Rigging Gaffer |
| Lighting | Herb DeWaal | Rigging Grip |
| Lighting | Rod Haney | Rigging Grip |
| Lighting | Scott Kozak | Rigging Grip |
| Camera | Joseph Lederer | Still Photographer |
| Camera | David Dolsen | Still Photographer |
| Camera | Ian Seabrook | Underwater Director of Photography |
| Visual Effects | Yogesh Bhavsar | Creature Technical Director |
| Visual Effects | Avijit Das | Creature Technical Director |
| Visual Effects | Eric Moliner | Creature Technical Director |
| Visual Effects | Mischa Kolbe | Creature Technical Director |
| Visual Effects | Fazil Ahmed | Creature Technical Director |
| Visual Effects | Sianoosh Nasiriziba | Lead Animator |
| Visual Effects | Andrew Park | Lead Animator |
| Visual Effects | Amit Narwani | Matchmove Supervisor |
| Visual Effects | K.G. Ginu | Modeling |
| Visual Effects | James Galen Clark | Modeling |
| Crew | Daniel Kwon | Motion Capture Artist |
| Visual Effects | C. Michael Neely | Pre-Visualization Supervisor |
| Visual Effects | Steve Yamamoto | Pre-Visualization Supervisor |
| Visual Effects | Barnes Wheeler | VFX Editor |
| Visual Effects | Nick Ghizas | Visual Effects Coordinator |
| Visual Effects | Rasghania Bharat | Visual Effects Coordinator |
| Visual Effects | Kotamraju Karthik | Visual Effects Coordinator |
| Visual Effects | Sammy Shikaze | Visual Effects Coordinator |
| Visual Effects | Connor Smith | Visual Effects Coordinator |
| Visual Effects | Lesly Cazares | Visual Effects Coordinator |
| Visual Effects | Thomas Elder-Groebe | Visual Effects Producer |
| Visual Effects | Sabrina Gagnon | Visual Effects Producer |
| Visual Effects | Anton Agerbo | Visual Effects Producer |
| Visual Effects | Michael Brazelton | Visual Effects Supervisor |
| Visual Effects | Dan Glass | Visual Effects Supervisor |
| Visual Effects | Sean Konrad | Visual Effects Supervisor |
| Visual Effects | Daniel Macarin | Visual Effects Supervisor |
| Visual Effects | Damiano Moltisanti | Visual Effects Technical Director |
| Visual Effects | Thomas Dotheij | Visual Effects Technical Director |
| Visual Effects | Phoenix Woung-Bi Lee | Visual Effects Technical Director |
| Costume & Make-Up | Beverlee June Fix | Assistant Costume Designer |
| Costume & Make-Up | Monique McRae | Assistant Costume Designer |
| Costume & Make-Up | Gwendolyn Stukely | Assistant Costume Designer |
| Costume & Make-Up | Lana S. Krause | Costume Coordinator |
| Costume & Make-Up | Janice MacIsaac | Costume Supervisor |
| Costume & Make-Up | Carolyn Bentley | Set Costumer |
| Costume & Make-Up | Cat Mudryk | Set Costumer |
| Costume & Make-Up | Farrahlyn Owen | Set Costumer |
| Costume & Make-Up | Nicola Ryall | Set Costumer |
| Production | Johnny Gidcomb | ADR Voice Casting |
| Production | Riva Cahn Thompson | Casting Associate |
| Production | Raylin Sabo | Casting Associate |
| Production | Ko Iwagami | Casting Consultant |
| Production | Corinne Clark | Casting |
| Production | Jennifer Page | Casting |
| Production | Yumi Takada | Casting Consultant |
| Crew | Rob Fournier | Armorer |
| Crew | Jeremy Muir | Armorer |
| Crew | Ric Walkington | Armorer |
| Crew | Paul Becker | Choreographer |
| Directing | Ana Oparnica Sebal | Script Supervisor |
| Crew | Lorraine Jamison | Unit Publicist |
| Writing | Ryan Reynolds | Screenplay |
| Crew | Sala Baker | Stunts |
| Editing | Dirk Westervelt | Editor |
| Sound | Tyler Bates | Original Music Composer |
| Crew | Joe Doserro | Stunt Driver |
| Costume & Make-Up | Anne Carroll | Hair Department Head |
| Costume & Make-Up | Bill Corso | Makeup Designer |
| Crew | Rebeccah Delchambre | Makeup Effects |
| Crew | Felix Fox | Makeup Effects |
| Costume & Make-Up | Katie Goett | Special Effects Makeup Artist |
| Costume & Make-Up | Richard Kohlen | Hairstylist |
| Costume & Make-Up | Harlow MacFarlane | Special Effects Makeup Artist |
| Costume & Make-Up | Geoff Redknap | Special Effects Makeup Artist |
| Costume & Make-Up | Bronwyne Sloley | Special Effects Makeup Artist |
| Directing | Paul Barry | First Assistant Director |
| Art | Niki Charalambopoulos | Painter |
| Art | Jason Claridge | Painter |
| Art | Daniel Columbie | Prop Designer |
| Art | Stian Dahlslett | Concept Artist |
| Crew | Joel Hansen | Carpenter |
| Art | Todd Harris | Storyboard Artist |
| Art | Paul Jenkinson | Lead Set Dresser |
| Art | Benjamin Last | Concept Artist |
| Art | Aaron McBride | Concept Artist |
| Art | Kouji Tajima | Concept Artist |
| Sound | Ronald Eng | Dialogue Editor |
| Sound | Tim Gomillion | Sound Recordist |
| Sound | David Grimaldi | Sound Effects Editor |
| Sound | Sean Massey | Supervising Dialogue Editor |
| Sound | Chuck Michael | Sound Designer |
| Sound | John Morris | Foley Supervisor |
| Sound | Mark Noda | Sound Mixer |
| Sound | Mark P. Stoeckinger | Supervising Sound Editor |
| Sound | Martyn Zub | Sound Designer |
| Visual Effects | Mike Vézina | Special Effects Supervisor |
| Crew | Matt Blouin | Visual Effects Editor |
| Lighting | Matt Bonin | Rigging Grip |
| Editing | Matt Absher | First Assistant Editor |
| Editing | Jim Carretta | First Assistant Editor |
| Editing | Daniel M. Nussbaum | First Assistant Editor |
| Sound | Ted Caplan | Music Editor |
| Sound | John Houlihan | Music Supervisor |
| Sound | Drew Krassowski | Orchestrator |
| Crew | Joi Harris | Stunt Double |
| Crew | Joi Harris | In Memory Of |
