When virtually all of the residents of Piedmont, New Mexico, are found dead after the return to Earth of a space satellite, the head of the US Air Force's Project Scoop declares an emergency. A group of eminent scientists led by Dr. Jeremy Stone scramble to a secure laboratory and try to first isolate the life form while determining why two people from Piedmont - an old alcoholic and a six-month-old baby - survived. The scientists methodically study the alien life form unaware that it has already mutated and presents a far greater danger in the lab, which is equipped with a nuclear self-destruct device designed to prevent the escape of dangerous biological agents.
| Writing | Nelson Gidding | Screenplay |
| Writing | Michael Crichton | Novel |
| Sound | Gil Mellé | Original Music Composer |
| Directing | Robert Wise | Director |
| Production | Robert Wise | Producer |
| Camera | Richard H. Kline | Director of Photography |
| Editing | Stuart Gilmore | Editor |
| Editing | John W. Holmes | Editor |
| Costume & Make-Up | Larry Germain | Hairstylist |
| Art | Boris Leven | Production Design |
| Visual Effects | Douglas Trumbull | Visual Effects |
| Costume & Make-Up | Helen Colvig | Costume Design |
| Art | Ruby R. Levitt | Set Decoration |
| Visual Effects | Albert Whitlock | Visual Effects |
| Art | William H. Tuntke | Art Direction |
| Costume & Make-Up | Bud Westmore | Makeup Artist |
| Visual Effects | Jamie Shourt | Visual Effects |
| Camera | Kenneth Smith | Grip |
| Sound | James R. Alexander | Sound |
| Sound | Ronald Pierce | Sound |
| Sound | Waldon O. Watson | Sound |
| Crew | Whitey McMahon | Special Effects |
