Dr. Frankenstein and her assistant, Dr. Yanco, are going to bring one of their experiments to life in Santo Vs. Frankenstein's Daughter. She intends to use a monster named Ursus to do her evil bidding. Using a youth serum to retain their vitality, the doctors set their sights upon none other than El Santo. They need his super human blood to regenerate a stronger youth serum. They kidnap Santo's goddaughter, Norma and lure him into Dr. Frankenstein's lab where he is captured and enslaved. Will Santo make it out alive?
You can now watch Santo vs. Frankenstein's Daughter online on the following streaming providers in the United States.
| Production | Guillermo Calderón | Producer |
| Directing | Miguel M. Delgado | Director |
| Camera | Raúl Martínez Solares | Director of Photography |
| Production | El Santo | Producer |
| Editing | Jorge Busto | Editor |
| Writing | Fernando Osés | Story |
| Writing | Fernando Osés | Adaptation |
| Editing | Joaquín Ceballos | Assistant Editor |
| Art | José Rodríguez Granada | Production Design |
| Art | Adalberto López | Set Decoration |
| Costume & Make-Up | Román Juárez | Makeup Artist |
| Sound | Gustavo César Carrión | Music Director |
