Mutant snakes survived a terrorist attack on a government laboratory, and they now threaten the town of Santa Mira Springs, California. Seismic activity has brought snakes to the surface, where residents are being bitten. Victims can transmit the virus to healthy persons. The military puts the town under quarantine. Local physicians try to control the epidemic, while the military is primarily concerned with keeping the virus a secret.
| Directing | Fred Olen Ray | Director |
| Writing | Sean McGinly | Writer |
| Writing | Dan Golden | Writer |
| Production | Alan B. Bursteen | Executive Producer |
| Production | Alison Semenza | Producer |
| Production | Jim Wynorski | Producer |
| Sound | Neal Acree | Music |
| Camera | Andrea V. Rossotto | Director of Photography |
| Editing | Randy Carter | Editor |
| Art | Steve Ralph | Production Design |
| Costume & Make-Up | Robert Constant | Costume Design |
| Art | Linda Louise Sheets | Art Direction |
| Costume & Make-Up | Stefanie Owens | Makeup Department Head |
| Crew | Bob Bragg | Stunt Coordinator |
| Crew | Patrick J. Statham | Stunts |
| Crew | Ellen Statham | Stunts |
| Crew | Robert Powell | Stunts |
| Crew | Paul E. Short | Stunts |
| Crew | Steve Hart | Stunts |
| Crew | Matthew R. Anderson | Stunts |
| Camera | Mac Ahlberg | Second Unit Director of Photography |
| Camera | Gary Graver | Additional Photography |
| Camera | Donald G. Jackson | Additional Photography |
