A runaway train, transporting deadly, toxic chemicals, is barreling down on Stanton, Pennsylvania, and proves to be unstoppable until a veteran engineer and young conductor risk their lives to try and stop it with a switch engine.
| Production | Alex Young | Producer |
| Production | Chris Ciaffa | Executive Producer |
| Production | Rick Yorn | Executive Producer |
| Production | Tony Scott | Producer |
| Production | Jeff Kwatinetz | Executive Producer |
| Production | Eric McLeod | Producer |
| Production | Julie Yorn | Producer |
| Production | Mimi Rogers | Producer |
| Directing | Tony Scott | Director |
| Writing | Mark Bomback | Writer |
| Camera | Ben Seresin | Director of Photography |
| Editing | Chris Lebenzon | Editor |
| Editing | Robert Duffy | Editor |
| Art | Drew Boughton | Art Direction |
| Production | Denise Chamian | Casting |
| Art | Rosemary Brandenburg | Set Decoration |
| Art | Chris Seagers | Production Design |
| Art | Denise Hudson | Art Direction |
| Costume & Make-Up | Stacy Horn | Costume Supervisor |
| Art | Dawn Swiderski | Art Direction |
| Costume & Make-Up | Penny Rose | Costume Design |
| Art | Julian Ashby | Art Direction |
| Costume & Make-Up | Edouard F. Henriques | Makeup Department Head |
| Camera | Robert Zuckerman | Still Photographer |
| Sound | William B. Kaplan | Production Sound Mixer |
| Sound | Nerses Gezalyan | Sound Mixer |
| Sound | Harry Gregson-Williams | Original Music Composer |
| Camera | Mark Meyers | Steadicam Operator |
| Visual Effects | Elayaraja | Visual Effects Coordinator |
| Crew | Jose Marra | Visual Effects Editor |
| Art | Carla S. Nemec | Art Department Coordinator |
| Art | Mike Villarino | Construction Coordinator |
| Art | Eugene McCarthy | Property Master |
| Camera | John T. Connor | Camera Operator |
| Lighting | Dan Jarrell | Rigging Grip |
| Crew | Bret St. Clair | CG Supervisor |
| Visual Effects | Duane Floch | Pre-Visualization Supervisor |
| Costume & Make-Up | Sandra Linn Koepper | Makeup Artist |
| Crew | Kosta Saric | Visual Effects Editor |
| Visual Effects | John Frazier | Special Effects Supervisor |
| Crew | Joe Pancake | Special Effects Coordinator |
| Costume & Make-Up | Debi Young | Makeup Artist |
| Visual Effects | Paul O'Shea | Visual Effects Supervisor |
| Costume & Make-Up | Carl Fullerton | Makeup Artist |
| Lighting | Skip Haswell | Rigging Grip |
| Visual Effects | Kimberly Covate | Visual Effects Producer |
| Camera | Michael Wahl | Dolly Grip |
| Costume & Make-Up | Yolanda Toussieng | Hair Department Head |
| Costume & Make-Up | Danny Moumdjian | Hair Designer |
| Costume & Make-Up | Diane Dixon | Hairstylist |
| Crew | Mark Mahoney | Tattooist |
| Costume & Make-Up | Larry M. Cherry | Hairstylist |
| Costume & Make-Up | Natasha Ladek | Wigmaker |
| Lighting | Joshua Stern | Rigging Gaffer |
| Costume & Make-Up | Wyatt Belton | Key Hair Stylist |
| Camera | Darin Moran | Camera Operator |
| Costume & Make-Up | Diane Heller | Key Makeup Artist |
| Costume & Make-Up | Rachel Kick | Makeup Artist |
| Art | Christina Romney-Glotzer | Art Department Coordinator |
| Visual Effects | Diana Cheng | Visual Effects Coordinator |
| Art | Dale DeStefani | Construction Coordinator |
| Camera | Martin Schaer | Camera Operator |
| Visual Effects | Michael Shelton | Lead Animator |
| Lighting | Scott Sprague | Lighting Technician |
| Lighting | Simone Perusse | Lighting Technician |
| Crew | Jason Schugardt | CG Supervisor |
| Crew | Bruno Van Zeebroeck | Special Effects Coordinator |
| Camera | John Skotchdopole | Camera Operator |
| Camera | Ralph Del Castillo | Dolly Grip |
| Lighting | Pat Dames | Rigging Grip |
| Sound | Mark P. Stoeckinger | Supervising Sound Editor |
| Lighting | Jack English | Gaffer |
| Crew | Chuck Picerni Jr. | Stunt Coordinator |
| Crew | Gary Powell | Stunt Coordinator |
| Crew | Clay Cullen | Stunts |
| Crew | Michael Runyard | Stunt Driver |
| Crew | Keith Campbell | Stunt Driver |
| Crew | Jeremy Fry | Stunt Double |
