In Arborville, California, three high school students try to protect their hometown from a gelatinous alien life form that engulfs everything it touches. The first to discover the substance and live to tell about it, the trio witness the Blob destroying an elderly man, then it growing to a terrifying size. But no one else has seen the goo, and the police refuse to believe the kids without proof.
| Directing | Chuck Russell | Director |
| Writing | Chuck Russell | Screenplay |
| Writing | Frank Darabont | Screenplay |
| Production | Elliott Kastner | Producer |
| Production | Andre Blay | Executive Producer |
| Sound | Michael Hoenig | Original Music Composer |
| Camera | Mark Irwin | Director of Photography |
| Editing | Tod Feuerman | Editor |
| Editing | Terry Stokes | Editor |
| Production | Johanna Ray | Casting |
| Costume & Make-Up | Joseph A. Porro | Costume Design |
| Production | Jack H. Harris | Producer |
| Art | Craig Stearns | Production Design |
| Art | Jeff Ginn | Art Direction |
| Art | Anne H. Ahrens | Set Decoration |
| Costume & Make-Up | Sanja Milković Hays | Costume Supervisor |
| Visual Effects | Kent Burton | Animation |
| Costume & Make-Up | Steven Frank | Hairstylist |
| Crew | John Caglione Jr. | Makeup Effects |
| Crew | Mike Smithson | Makeup Effects |
| Costume & Make-Up | Marlene Stoller | Wigmaker |
| Costume & Make-Up | Becky Ochoa | Wigmaker |
| Costume & Make-Up | Melinda Kennemore | Wigmaker |
| Costume & Make-Up | Max Alvarez | Wigmaker |
| Crew | Tony Gardner | Animatronic and Prosthetic Effects |
| Crew | Blaine Converse | Post Production Supervisor |
| Art | Michael Reinhart | Construction Coordinator |
| Crew | Michael D. Costello | Scenic Artist |
| Crew | Amanda J. Flick | Scenic Artist |
| Crew | Gerald Labitts | Scenic Artist |
| Crew | Renee Prince | Scenic Artist |
| Crew | Kip Sawyer | Scenic Artist |
| Crew | Ildiko Toth | Scenic Artist |
| Art | Brian Wade | Sculptor |
| Art | Mark Siegel | Sculptor |
| Art | Shawn McEnroe | Sculptor |
| Art | Mitch Devane | Sculptor |
| Art | Gary F. Steele | Set Designer |
| Art | Sally Thornton | Set Designer |
| Art | John D. Kretschmer | Leadman |
| Sound | Bruce Stambler | Supervising Sound Editor |
| Sound | Frank A. Fuller Jr. | Sound Designer |
| Sound | Gordon Ecker | Supervising Sound Editor |
| Sound | Wayne Heitman | Sound Re-Recording Mixer |
| Sound | Matthew Iadarola | Sound Re-Recording Mixer |
| Sound | Stanley Kastner | Sound Re-Recording Mixer |
| Sound | Becky Sullivan | ADR & Dubbing |
| Sound | Gregg Barbanell | Foley |
| Crew | Jody Rogers | Visual Effects Editor |
| Visual Effects | Keith Shartle | Visual Effects Producer |
| Visual Effects | Hoyt Yeatman | Visual Effects Supervisor |
| Crew | Steve Holladay | Stunt Coordinator |
| Camera | Eric J. Goldstein | Camera Operator |
| Camera | László Regos | Steadicam Operator |
| Camera | Marsha Blackburn | Still Photographer |
| Lighting | Jock Brandis | Gaffer |
| Lighting | Austin Goss | Best Boy Electric |
| Sound | Richard Whitfield | Music Editor |
| Crew | Lawrence J. Romanoff | Transportation Coordinator |
| Directing | Helen Caldwell | Script Supervisor |
| Production | Gerrit V. Folsom | Location Manager |
| Crew | Rachael Horovitz | Unit Publicist |
| Crew | Dennis Scott | Stunts |
| Directing | Josh McLaglen | First Assistant Director |
| Camera | J. Tom Archuleta | Second Assistant Camera |
| Costume & Make-Up | Kathryn Fenton | Key Makeup Artist |
| Costume & Make-Up | Janeen Davis | Makeup & Hair Assistant |
| Art | Joseph H. Catmull | Construction Foreman |
| Art | David B. Long | Construction Foreman |
| Art | Lauren York | Construction Foreman |
| Art | J.J. May | Property Master |
| Crew | Tony Allard | Prop Maker |
| Art | Steve Blakney | Set Dresser |
| Art | Ross Harpold | Set Dresser |
| Art | Barbara Kahn | Set Dresser |
| Art | Sandra Sweeney | Set Dresser |
| Art | Portia Perry | Set Painter |
| Art | Pete von Sholly | Storyboard Artist |
| Camera | Loren Corl | Dolly Grip |
| Lighting | Neil Holcomb | Electrician |
| Lighting | Don MacLean | Electrician |
| Lighting | Jay W. Yowler | Electrician |
| Lighting | Richard M. Butkus Jr. | Electrician |
| Camera | Findlay Bunting | First Assistant Camera |
| Camera | Michael Condro | First Assistant Camera |
| Camera | Ian Fox | First Assistant "B" Camera |
| Camera | Stephen Wong | First Assistant "B" Camera |
| Camera | Thomas Browne | Grip |
| Camera | Pascal Franchot | Grip |
| Camera | Dwight Locke | Grip |
| Camera | Mike Maday | Grip |
| Camera | Bob Myers | Grip |
| Camera | Terry O'Brien | Grip |
| Camera | Caleb Edwards | Key Grip |
| Lighting | Kevin Cook | Rigging Grip |
| Crew | Mark Setrakian | Animatronics Designer |
| Costume & Make-Up | Nazhat Hester | Costumer |
| Costume & Make-Up | Garet Reilly | Costumer |
| Costume & Make-Up | Scott Tomlinson | Costumer |
| Production | Barbara Harris | ADR Voice Casting |
| Production | Eric DaRe | Casting Assistant |
| Production | Donna Morong | Casting Assistant |
| Production | Mary Santiago | Extras Casting |
| Editing | Rebekah Rudd | First Assistant Editor |
| Production | Carol Kravetz | Production Coordinator |
| Production | Florian Schereck | Production Accountant |
| Art | Dan Curry | Title Designer |
| Visual Effects | Jeff Burks | Animation Supervisor |
| Crew | Kathy Chasen-Hay | Visual Effects Editor |
| Crew | C. Marie Davis | Visual Effects Editor |
| Visual Effects | Don Dow | Visual Effects Camera |
| Visual Effects | Brian Adams | Visual Effects Production Assistant |
| Visual Effects | Beau Windham | Visual Effects Production Assistant |
| Visual Effects | Dana Miller Schornstein | Visual Effects Production Manager |
| Sound | Greg Steele | Sound Recordist |
| Sound | Mark 'Frito' Long | Sound Recordist |
| Art | Douglas S. Turner | Sculptor |
| Visual Effects | Douglas S. Turner | Effects Supervisor |
| Crew | Freddie Hice | Stunts |
| Crew | Debby Porter | Stunts |
| Crew | Ric Roman Waugh | Stunts |
| Crew | Janet Brady | Stunts |
| Crew | Bobby Burns | Stunts |
| Crew | Pat Romano | Stunts |
| Writing | Irvine H. Millgate | Original Concept |
| Writing | Kay Linaker | Original Film Writer |
| Writing | Theodore Simonson | Original Film Writer |
| Crew | Gene Hartline | Stunts |
