At the Tromaville Institute of Technology's nuclear plant, Prof. Holt has perfected "subhumanoids": living beings without emotions who perform menial tasks. When school reporter Roger Smith meets a beautiful subhumanoid named Victoria, they fall in love and he becomes determined to save her and the school from a giant mutant squirrel, Tromie.
You can now watch Class of Nuke 'Em High 2: Subhumanoid Meltdown online on the following streaming providers in the United States.
| Writing | Matt Unger | Original Story |
| Directing | Eric Louzil | Director |
| Writing | Carl Morano | Original Story |
| Writing | Carl Morano | Screenplay |
| Writing | Matt Unger | Screenplay |
| Writing | Lloyd Kaufman | Screenplay |
| Writing | Jeffrey W. Sass | Screenplay |
| Writing | Mark F. Roling | Screenplay |
| Writing | Lloyd Kaufman | Original Story |
| Writing | Eric Louzil | Screenplay |
| Camera | Donald G. Jackson | Second Unit Director of Photography |
| Production | Lloyd Kaufman | Producer |
| Crew | Ron Chapman | Cinematography |
| Production | Carl Morano | Associate Producer |
| Costume & Make-Up | Kaptain | Costume Design |
| Sound | Bob Mithoff | Music |
| Production | Michael Herz | Producer |
| Editing | Gordon Grinberg | Editor |
