Bill Dane and Banty quit Kell's outlaw gang. When Dane prevents Kell and his men from getting a bullion shipment, he is made Sheriff. Learning Dane is Sheriff, Kell and gang return, force Dane to give them the bullion, and make Dane a prisoner. Escaping, Dane trails the gang and engages them in a gunfight while his horse Tarzan goes for help.
Mary Thorne is the quarter-breed daughter of prospector Marshall Thorne. She has just returned from college and when a pair of hunters, Mark Hamilton and Chester Martin, come along, she decides it would be fun to dress in native garb and fool them. Both men find themselves attracted to her, even though Indians were taboo for whites in the racist days of the 1910s.
A horse called Brilliant is the only one who knows the location of a gold mine. When Brilliant's owner is killed, the trio known as the Three Mesquiteers (Bob Steele, Tom Tyler and Jimmie Dodd) are mistakenly arrested for the murder.
An evil deputy is using Indian half-breeds to rustle cattle. This causes trouble between the cattlemen and Indians. Hoppy, Windy and Lucky see that justice is served. Songs abound.
Mickey walks into the tavern where Minnie is dancing, and begins to dance and play piano himself. Pegleg Pete comes in and treats Minnie badly. Mickey tries to defend her, but Pete steals her away. Mickey, riding Horace Horsecollar, gives chase. He manages to throw Pete off a cliff.
Johnny and Alibi try to straighten out a hostile young boy whose older brother was a notorious stagecoach bandit. When a gang of thieves try to strong-arm the kid into revealing the whereabouts of the stolen loot, Johnny and Alibi come to the rescue. There's a cursory romantic subplot involving heroine Mary and Barstow.
The Dale's need money for their sick mother and Bart Travis, having found gold, says he will provide it. Duke Remsden learns of the strike and waylays Buzz Dale as he tries to record Bart's deed. Then dressed as Bart, Duke kills and robs a man. With the Sheriff after Bart, Buzz escapes capture, finds the clothes worn to impersonate Bart, and heads for the Sheriff.
Unknown to Joan Manning, her trading post partner Weathers is operating a counterfeiting ring. When miner Jim Smithers brings his gold dust in, Weathers pays him off in counterfeit money. Jim's drunken brother, Bill, comes to the post and Weathers hears him say that Jim is leaving the area for good. Weathers sends Hawks to kill Jim and retrieve the bogus money. RCMP Sergeant Renfrew and Constable Kelly find Jim's body, and Renfrew hurries for Jim's cabin to search it. He is attacked by Weathers' men who have found the money. Renfrew is suspicious when Bill Smithers body is found, supposedly a suicide, with a note he had burned the money. This leads the Mounties to suspect counterfeiting. Kelly follows Manti, an Indian who works for Weathers, to the gang's hideout and is captured. But Renfrew is trailing Kelly.
Idaho, returning to the area he left as a boy, gets in the middle of a range feud. He takes the side of Endicott. On the other side is Hollister who is unaware that Idaho is his long lost son.
Based on the Lucky Luke comic books; Lucky Luke (Terence Hill) arrives into a tiny western town, Purgatory, and is asked to escort 12 mail order brides from another town, where some bandits get on their trail.
A gang of bad men terrorizes the country. Their revenge is directed against the daughter of a rancher who defies the leader. The attempt to abduct the girl is foiled by Jim Bart.
A big city reporter visits a Colorado ranch to write an article for his paper and is surprised to learn that real cowboys are not as glamorous as Hollywood portrays, He then experiences first hand the day to day life an authentic cowboy.