A shipwrecked sailor stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.
| Directing | John Frankenheimer | Director |
| Writing | Richard Stanley | Screenplay |
| Writing | H.G. Wells | Novel |
| Production | Edward R. Pressman | Producer |
| Sound | Gary Chang | Original Music Composer |
| Art | Ian Gracie | Art Direction |
| Writing | Ron Hutchinson | Screenplay |
| Production | Valerie McCaffrey | Casting |
| Production | Claire Rudnick Polstein | Executive Producer |
| Camera | William A. Fraker | Director of Photography |
| Editing | Adam P. Scott | Editor |
| Art | Graham 'Grace' Walker | Production Design |
| Production | Tim Zinnemann | Executive Producer |
| Editing | Paul Rubell | Editor |
| Visual Effects | Kevin Scott Mack | Visual Effects Supervisor |
| Sound | David Lee | Sound Recordist |
| Costume & Make-Up | Gary Archer | Prosthetics |
| Production | James McTeigue | Production Assistant |
| Editing | Thom Noble | Editor |
| Art | Lesley Crawford | Set Decoration |
| Art | Beverley Dunn | Set Decoration |
| Costume & Make-Up | Norma Moriceau | Costume Design |
| Directing | James Sbardellati | First Assistant Director |
| Camera | Ian Bird | Best Boy Grip |
| Camera | Peter Sorel | Set Photographer |
