After solving their last mystery at Spooky Island, the Mystery Inc. gang is back in Coolsville, where they are being honored with their very own exhibit at the Coolsonian Criminology Museum. However, when a masked villain steals costumes of classic monsters on display and brings them to life, the gang must come out of retirement to solve the case.
| Production | Kelley Smith-Wait | Executive Producer |
| Editing | Kent Beyda | Editor |
| Production | Richard Suckle | Producer |
| Sound | David Newman | Original Music Composer |
| Camera | Oliver Wood | Director of Photography |
| Production | Charles Roven | Producer |
| Production | Joseph Barbera | Executive Producer |
| Directing | Raja Gosnell | Director |
| Production | Brent O'Connor | Executive Producer |
| Visual Effects | Chris Lentz | Animation |
| Visual Effects | Andrew Arnett | Animation |
| Visual Effects | Steve Cady | Animation |
| Visual Effects | Jeff Croke | Animation |
| Visual Effects | Kristin Solid | Animation |
| Visual Effects | Brian Dowrick | Animation |
| Visual Effects | Hugo Dominguez | Visual Effects |
| Crew | Bill Haller | Supervising Animator |
| Visual Effects | Matt Williames | Animation |
| Visual Effects | Steve Harwood | Animation |
| Visual Effects | Leigh H. Rens | Animation |
| Visual Effects | Angie Jones | Animation |
| Directing | Steeve Boulianne | Layout |
| Production | James Gunn | Co-Producer |
| Production | Alan Glazer | Co-Producer |
| Production | Mary Vernieu | Casting |
| Production | Richard Cowan | Associate Producer |
| Crew | James Bamford | Stunts |
| Crew | J.J. Makaro | Stunt Coordinator |
| Art | Daphne Klebe | Art Department Coordinator |
| Camera | Glen A. Dickson | Additional Camera |
| Art | Don MacAulay | Art Direction |
| Art | Mira Caveno | Set Designer |
| Art | Shepherd Frankel | Supervising Art Director |
| Writing | William Hanna | Characters |
| Art | Tedd Kuchera | Set Decoration |
| Art | Brad Oleksy | Greensman |
| Art | Brent Gloeckler | Sculptor |
| Camera | Steven J. Winslow | Camera Technician |
| Writing | Joseph Barbera | Characters |
| Art | Constantine Sekeris | Conceptual Design |
| Camera | Rick Allen | Grip |
| Art | Peter Ochotta | Art Department Assistant |
| Art | Michael N. Wong | Art Direction |
| Camera | Sandes Ashe | First Assistant Camera |
| Costume & Make-Up | Leesa Evans | Costume Design |
| Art | Warren Dunlop | Construction Foreman |
| Art | Bill Boes | Production Design |
| Art | Brian Shell | Construction Coordinator |
| Art | John Alvarez | Assistant Art Director |
| Camera | Diyah Pera | Still Photographer |
| Crew | Michael Shand | CGI Supervisor |
| Crew | Tony Swatton | Armorer |
| Crew | Joey Lessard | CG Supervisor |
| Crew | Joan Kelley Bierman | Post Production Supervisor |
| Crew | Cody Laudan | Utility Stunts |
| Lighting | Christopher Charles Kempinski | Lighting Technician |
| Production | Daniel R. Chavez | Executive In Charge Of Post Production |
| Visual Effects | Chris Bond | Visual Effects Supervisor |
| Camera | Dan Mannix | Steadicam Operator |
| Crew | Dwane McIsaac | Chef |
| Crew | Lance Johnson | Property Master |
| Crew | Steve Linn | Systems Administrators & Support |
| Sound | Gregory Jamrok | Orchestrator |
| Visual Effects | David Zbriger | I/O Supervisor |
| Visual Effects | Mike Splatt | Special Effects Supervisor |
| Crew | Jim Rankin | Craft Service |
| Sound | Darren Higman | Music Supervisor |
| Visual Effects | Conrad Dueck | 3D Supervisor |
| Costume & Make-Up | Bill Terezakis | Prosthetic Supervisor |
| Camera | Tim Arasheben | Helicopter Camera |
| Costume & Make-Up | Luisa Dalmagro | Set Costumer |
| Sound | Scott Wolf | Sound Designer |
| Visual Effects | Keith Hunter | Modeling |
| Costume & Make-Up | Anji Bemben | Hairstylist |
| Costume & Make-Up | Gitte Axen | Makeup Artist |
| Crew | Chris Bradford | Security |
| Crew | Daniel Arkin | Visual Effects Editor |
| Sound | Kelly Zombor | Boom Operator |
| Sound | Michael D. Wilhoit | Supervising Sound Editor |
| Visual Effects | Melany Bourgouin | Visual Effects Coordinator |
| Sound | Karen Schell | Sound |
| Crew | Rick Rasmussen | Picture Car Coordinator |
| Crew | David Allinson | Special Effects Coordinator |
| Crew | Steve Ellis | Transportation Captain |
| Sound | Jeff Glueck | Sound Engineer |
| Production | Juliet Verni | Production Coordinator |
| Production | Rif Dagher | Researcher |
| Crew | Laura Boddington | Stand In |
| Lighting | Cory Hodson | Rigging Gaffer |
| Visual Effects | Benton Jew | Creature Design |
| Visual Effects | Laide Agunbiade | Digital Compositors |
| Crew | Patrick Booker | Carpenter |
| Crew | Ray Evans | Driver |
| Crew | Fernando Favila | Makeup Effects |
| Crew | Ivan Neulander | Software Engineer |
| Production | Brent O'Connor | Unit Production Manager |
| Lighting | Raymond Chen | Lighting Supervisor |
| Production | Charles Lyall | Production Manager |
| Editing | Valance Eisleben | Editorial Services |
| Production | Bill Draper | Executive In Charge Of Production |
| Sound | Kerry Ann Carmean | Sound Effects Editor |
| Sound | David Husby | Production Sound Mixer |
| Crew | Andy Armstrong | Stunt Coordinator |
| Crew | László Sebõ | Technical Supervisor |
| Crew | Ronald Schlueter | Video Assist Operator |
| Production | Kirk Johns | Location Manager |
| Production | Mandy Butler | Production Accountant |
| Production | Julia Frittaion | Publicist |
| Sound | Mark Kenna | Dolby Consultant |
| Sound | Chris Hogan | Sound Editor |
| Visual Effects | August Hall | Visual Development |
| Crew | Nick Allen | Stunts |
| Lighting | John Lai | Lighting Artist |
| Sound | Markus Czyzewski | Music Editor |
| Crew | Todd Shifflett | Digital Effects Supervisor |
| Editing | Matt Diezel | Assistant Editor |
| Crew | Peter Huff | Transportation Coordinator |
| Lighting | Tim Atkins | Gaffer |
| Lighting | Ronnie Baran | Best Boy Electric |
| Visual Effects | Mathieu Blouin | Animation Supervisor |
| Crew | Erika A. McKee | Digital Producer |
| Visual Effects | Stephanie Allen | Visual Effects Producer |
| Sound | David Kudell | Assistant Sound Editor |
| Directing | Misha Bukowski | Third Assistant Director |
| Art | Santino Barile | Assistant Property Master |
| Costume & Make-Up | Alison Fraser | Costume Coordinator |
| Crew | Barrie Wells | Techno Crane Operator |
| Visual Effects | Kelvin Lee | Lead Animator |
| Directing | Richard Cowan | First Assistant Director |
| Sound | Jeff Carson | Supervising Music Editor |
| Editing | Mo Henry | Negative Cutter |
| Visual Effects | Adam de Bosch Kemper | Pre-Visualization Supervisor |
| Production | James McKenzie Moore | Casting Assistant |
| Sound | Kelly Oxford | ADR Editor |
| Art | Perry Battista | Lead Set Dresser |
| Camera | Todd Hlagi | Dolly Grip |
| Visual Effects | Mitch Gates | Visual Effects Technical Director |
| Art | Tracy B. Dunlop | Set Dresser |
| Production | Jody Chow | Assistant Production Coordinator |
| Sound | Diana Stata | Assistant Music Supervisor |
| Sound | Tom Boyd | Musician |
| Crew | Jim Filippone | Pilot |
| Sound | Laura Harris Atkinson | Supervising Dialogue Editor |
| Costume & Make-Up | Stacey Butterworth | Wig Designer |
| Directing | David Klohn | Second Assistant Director |
| Lighting | Dennis Brock | Chief Lighting Technician |
| Camera | Tim Hogan | Key Grip |
| Crew | Jason Crosby | Marine Coordinator |
| Camera | Jim Filippone | Helicopter Camera |
| Crew | Anne Fletcher | Choreographer |
| Editing | Lionel Barton | Colorist |
| Crew | Mike Larivee | Special Effects Technician |
| Production | Stephanie Boeke | Extras Casting |
| Costume & Make-Up | Tamar Ouziel | Assistant Makeup Artist |
| Directing | Joanna Moore | Second Second Assistant Director |
| Editing | Anthony Harris | Digital Color Timer |
| Art | Leah Hong | Graphic Designer |
| Crew | Jay Anderson | Generator Operator |
| Camera | Jim Bacon | Epk Producer |
| Editing | Ron Barr | Digital Intermediate Editor |
| Art | Shaun Bullied | Set Painter |
| Art | Brom | Storyboard Artist |
| Camera | Jim Van Dijk | First Assistant "A" Camera |
| Sound | David Newman | Conductor |
| Production | Suzie Bruce | Assistant Accountant |
| Production | Eve-Marie Gingras | Production Supervisor |
| Lighting | Jeff Hall | Assistant Chief Lighting Technician |
| Crew | Jim Bach | Playback Coordinator |
| Directing | Andy Armstrong | Second Assistant Director |
| Crew | Jim Dunn | Stunt Double |
| Camera | Harold Bernard | Second Assistant Camera |
| Visual Effects | Whitney Kitchen | Animation Coordinator |
| Visual Effects | Jacques Levesque | Compositing Supervisor |
| Crew | Jason Piccioni | Digital Supervisor |
| Production | Jamie Reid Tait | Second Assistant Production Coordinator |
| Sound | James Moriana | Foley Artist |
| Camera | Michael Lemmers | Best Boy Grip |
| Visual Effects | Will Cunningham | Compositing Artist |
| Art | Sean Lavoie | Paint Coordinator |
| Production | Errin Lally | Casting Coordinator |
| Lighting | Herb DeWaal | Key Rigging Grip |
| Costume & Make-Up | Rob Miller | Contact Lens Technician |
| Sound | Eric Gotthelf | ADR Mixer |
| Sound | Nerses Gezalyan | Foley Mixer |
| Editing | James Bluma | Assistant Editor |
| Production | Barbara Copp | Key Production Assistant |
| Costume & Make-Up | Elizabeth Beauchamp | Costumer |
| Costume & Make-Up | Cydney Cornell | Hairdresser |
| Visual Effects | Cheryl Budgett | 2D Supervisor |
| Production | Jina Johnson | Assistant Location Manager |
| Visual Effects | Marta Knudsen | Matte Painter |
| Crew | Darya Douglas-Andres | Special Effects Assistant |
| Visual Effects | Lindsay Hallett | Visual Effects Production Manager |
| Sound | Kimaree Long | Dialogue Editor |
| Sound | Michael Buffer | Musician |
| Writing | James Gunn | Writer |
| Crew | Doug Chapman | Stunts |
| Crew | Adam Shankman | Choreographer |
| Crew | Melissa R. Stubbs | Stunts |
| Directing | John MacCarthy | Second Unit First Assistant Director |
| Crew | Crystal Dalman | Stunts |
| Crew | Alette Falle | Stunts |
| Crew | Richard Brooks | Stunts |
| Crew | Ashlea Earl | Stunts |
| Crew | Nesta Chapman | Stunts |
| Crew | Jeff Sanca | Stunts |
