Leon S. Kennedy and Claire Redfield must battle a rogue warrior seeking revenge after unleashing the deadly G-Virus, whilst a mutated monster goes on a rampage.
| Directing | Makoto Kamiya | Director |
| Writing | Shoutarou Suga | Screenplay |
| Production | Haruhiro Tsujimoto | Executive Producer |
| Production | Hidenori Ueki | Co-Producer |
| Production | Hiroyuki Kobayashi | Producer |
| Sound | Koji Kasamatsu | Sound Designer |
| Sound | Yota Tsuruoka | Sound Director |
| Crew | Shinji Mikami | Video Game |
| Crew | Tokuro Fujiwara | Video Game |
| Crew | Kenichi Iwao | Video Game |
| Crew | Takahiro Arimitsu | Video Game |
| Writing | Hiroyuki Kobayashi | Story |
| Writing | Yoshiaki Hirabayashi | Story |
| Writing | Father | Story Editor |
| Production | Scott Dolph | Associate Producer |
| Production | Daisuke Gomi | Associate Producer |
| Production | Keiji Inafune | Executive Producer |
| Production | Seiji Iseda | Producer |
| Production | Aki Kiuchi | Associate Producer |
| Production | Taro Morishima | Producer |
| Production | Ivan C. Shih | Executive Producer |
| Production | Masao Takiyama | Executive Producer |
| Production | Toshi Tokumaru | Co-Executive Producer |
| Production | Mareo Yamada | Associate Producer |
| Sound | Tetsuya Takahashi | Original Music Composer |
| Editing | Ryuji Miyajima | Editor |
| Art | Shiho Tamura | Production Design |
| Costume & Make-Up | Kuniko Hôjô | Costume Design |
| Production | Alena Fang | Production Manager |
| Production | Kumiko Oguri | Production Manager |
| Production | Sareana Sun | Production Manager |
| Directing | Kentaro Fujisawa | Second Assistant Director |
| Directing | Gaku Nagao | First Assistant Director |
| Art | Takumi Sakura | Prop Designer |
| Directing | Nobuhito Sue | Layout |
| Sound | Les Claypool III | Dialogue Editor |
| Sound | Yoshiki Matsunaga | Sound Editor |
| Production | Yoshimi Sugiyama | Production Manager |
| Crew | Hiroki Ando | Compositor |
| Crew | Kazuhiro Asakawa | Compositor |
| Visual Effects | Wu Bin | VFX Artist |
| Lighting | Zhang Bei | Lighting Artist |
| Visual Effects | Stacy Chang | Modeling |
| Lighting | Peng Chao | Lighting Artist |
| Visual Effects | Hsin-Che Chen | Modeling |
| Visual Effects | Soyoung Cheng | Modeling |
| Visual Effects | Chaucer Chiu | Modeling |
| Lighting | Liu Dexin | Lighting Artist |
| Visual Effects | Atsushi Doi | CGI Director |
| Crew | Nobutaka Emoto | Compositor |
| Crew | Naoyuki Fujii | Compositor |
| Lighting | Le Gao | Lighting Artist |
| Visual Effects | Tsubasa Harikae | Compositing Lead |
| Lighting | Yifang He | Lighting Artist |
| Visual Effects | Yoshiaki Hirabayashi | Modelling Supervisor |
| Lighting | Zhang Hongkun | Lighting Artist |
| Visual Effects | Ni Hongtao | Animation |
| Crew | Satoshi Hakuzen | Stunts |
| Crew | Nobuhiro Inohara | Stunts |
| Crew | Jersey Maki Itosu | Stunts |
| Crew | Naohiro Kawamoto | Stunts |
| Directing | Hiroyuki Yoshida | Action Director |
| Visual Effects | Hiroki Ando | Animation |
| Visual Effects | Kazuhiro Asakawa | Character Designer |
| Production | Michelle Ladd | Casting Producer |
| Production | Thom Williams | Casting Producer |
| Production | Hiroyuki Yoshida | Casting Producer |
| Production | Yuuki Hashimoto | Post Production Producer |
| Editing | Narihiko Kôno | Assistant Editor |
| Directing | Father | Script Supervisor |
| Art | Shinji Nishikawa | Storyboard Artist |
| Art | Kiyoshi Okuyama | Storyboard Artist |
| Art | Hiromitsu Soma | Storyboard Artist |
| Crew | Koji Kawamoto | Stunts |
| Writing | Shinji Mikami | Original Story |
