A deadly airborne virus finds its way into the USA and starts killing off people at an epidemic rate. Col. Sam Daniels' job is to stop the virus spreading from a small town, which must be quarantined, and to prevent an over reaction by the White House.
| Editing | Lynzee Klingman | Editor |
| Production | Anne Kopelson | Executive Producer |
| Sound | James Newton Howard | Original Music Composer |
| Art | William Sandell | Production Design |
| Editing | Neil Travis | Editor |
| Writing | Laurence Dworet | Screenplay |
| Directing | Wolfgang Petersen | Director |
| Writing | Robert Roy Pool | Screenplay |
| Production | Arnold Kopelson | Producer |
| Production | Duncan Henderson | Executive Producer |
| Production | Wolfgang Petersen | Producer |
| Editing | William Hoy | Editor |
| Camera | Michael Ballhaus | Director of Photography |
| Sound | Michael C. Mason | Music Score Producer |
| Camera | Tom West | Best Boy Grip |
| Production | Jane Jenkins | Casting |
| Art | Nancy Patton | Art Direction |
| Art | Rosemary Brandenburg | Set Decoration |
| Costume & Make-Up | June Westmore | Makeup Artist |
| Production | Gail Katz | Producer |
| Costume & Make-Up | Erica Edell Phillips | Costume Design |
| Costume & Make-Up | Kathy W. Estocin | Hairstylist |
| Costume & Make-Up | Ellis Burman Jr. | Makeup Artist |
| Costume & Make-Up | Susan A. Cabral | Key Makeup Artist |
| Costume & Make-Up | Virginia G. Hadfield | Key Hair Stylist |
| Costume & Make-Up | Diane Pepper | Hairstylist |
| Production | Stephen Joel Brown | Co-Producer |
| Production | Nana Greenwald | Co-Producer |
| Production | Janet Hirshenson | Casting |
| Costume & Make-Up | Flo Avery | Hairstylist |
| Production | Sanford Panitch | Co-Producer |
| Art | Francis J. Pezza | Art Direction |
| Costume & Make-Up | Vivian McAteer | Hairstylist |
| Editing | Stephen E. Rivkin | Editor |
| Costume & Make-Up | Monty Westmore | Makeup Artist |
| Sound | Wylie Stateman | Supervising Sound Editor |
| Sound | Gregg Baxter | Supervising Sound Editor |
| Directing | Peter Kohn | First Assistant Director |
| Production | Dennis E. Jones | Production Manager |
| Directing | John Rusk | Second Assistant Director |
| Crew | Buddy Van Horn | Stunt Coordinator |
| Crew | Keith Tellez | Stunt Coordinator |
| Crew | Richard L. Blackwell | Stunts |
| Crew | Robby Robinson | Stunts |
| Crew | Shane Dixon | Stunts |
| Crew | Michael Runyard | Stunts |
| Crew | Charlie Brewer | Stunts |
| Art | Edward T. McAvoy | Assistant Art Director |
| Art | Carl J. Stensel | Set Designer |
| Art | Stella Vaccaro | Set Designer |
| Art | Tom Reta | Set Designer |
| Art | Eric W. Orbom | Set Designer |
| Directing | Dianne Dreyer | Script Supervisor |
| Art | Carl Aldana | Production Illustrator |
| Camera | Florian Ballhaus | "A" Camera Operator |
| Camera | Mark Emery Moore | "B" Camera Operator |
| Camera | Mark Emery Moore | Steadicam Operator |
| Camera | Mikael Glattes | First Assistant "A" Camera |
| Camera | Gary Dunham | First Assistant "B" Camera |
| Camera | Peter Sorel | Still Photographer |
| Camera | Jeffrey Thorin | Second Assistant Camera |
| Camera | Michael Martinez | Second Assistant Camera |
| Camera | Amy Hergoth | Second Assistant Camera |
| Lighting | James R. Tynes | Chief Lighting Technician |
| Lighting | John 'Fest' Sandau | Assistant Chief Lighting Technician |
| Lighting | Stanley L. Gonsales | Assistant Chief Lighting Technician |
| Lighting | Charlie McIntyre | Rigging Gaffer |
| Camera | J. Patrick Daily | Key Grip |
| Camera | Rex Hiscocks | Best Boy Grip |
| Camera | Kent H. Jorgensen | Dolly Grip |
| Camera | Eric Whitehead | Dolly Grip |
| Production | Delia Circelli | Production Office Coordinator |
| Directing | C.C. Barnes | Second Second Assistant Director |
| Crew | Rob Harris | Unit Publicist |
| Sound | Richard Lightstone | Production Sound Mixer |
| Sound | Gabriel Cubos | Boom Operator |
| Crew | William G. Flick | Cableman |
| Visual Effects | John Frazier | Special Effects Supervisor |
| Visual Effects | Mark Vargo | Visual Effects Supervisor |
| Art | Russell Bobbitt | Property Master |
| Costume & Make-Up | Tom Numbers | Costume Supervisor |
| Costume & Make-Up | Linda Serijan | Costume Supervisor |
| Art | Cal DiValerio | Construction Coordinator |
| Sound | Jim Weidman | Music Editor |
| Sound | Donald O. Mitchell | Sound Re-Recording Mixer |
| Sound | John T. Reitz | Sound Re-Recording Mixer |
| Sound | Michael Herbick | Sound Re-Recording Mixer |
| Sound | David E. Campbell | Sound Re-Recording Mixer |
| Sound | Frank A. Montaño | Sound Re-Recording Mixer |
| Sound | Gregg Rudloff | Sound Re-Recording Mixer |
| Sound | Artie Kane | Conductor |
| Sound | Todd Egan | Assistant Sound Editor |
| Sound | David Stanke | Assistant Sound Editor |
| Sound | Rickley W. Dumm | Assistant Sound Editor |
| Sound | John Rice | Assistant Sound Editor |
| Sound | Tim Groseclose | Assistant Sound Editor |
| Sound | Thomas O'Neil Younkman | Assistant Sound Editor |
| Sound | Robert Batha | First Assistant Sound Editor |
| Sound | Doc Kane | ADR Mixer |
| Sound | Thomas J. O'Connell | ADR Mixer |
| Sound | Gary A. Hecker | Foley Artist |
| Sound | Dan O'Connell | Foley Artist |
| Sound | James Ashwill | Foley Artist |
| Sound | Nerses Gezalyan | Foley Artist |
| Sound | Bill Voigtlander | ADR Editor |
| Sound | Laura Graham | ADR Editor |
| Sound | Holly Huckins | ADR Editor |
| Sound | Petra Bach | ADR Editor |
| Sound | Andrew London | ADR Editor |
| Sound | Craig S. Jaeger | Foley Editor |
| Sound | Hector C. Gika | Foley Editor |
| Sound | Bob Beher | Foley Editor |
| Sound | Lou Kleinman | Foley Editor |
| Sound | Clayton Collins | Dialogue Editor |
| Sound | Patrick J. Foley | Dialogue Editor |
| Sound | Michael P. Cook | Dialogue Editor |
| Sound | Chris Hogan | Dialogue Editor |
| Sound | Sarah Goldsmith | Dialogue Editor |
| Sound | Dan M. Rich | Dialogue Editor |
| Sound | Bruce Richardson | Supervising Sound Effects Editor |
| Sound | Scott Martin Gershin | Sound Effects Editor |
| Sound | Paul Timothy Carden | Sound Effects Editor |
| Sound | Dino DiMuro | Sound Effects Editor |
| Sound | Peter Michael Sullivan | Sound Effects Editor |
| Sound | Alan Rankin | Sound Effects Editor |
| Sound | Dan Hegeman | Sound Effects Editor |
| Sound | Jay B. Richardson | Sound Effects Editor |
| Sound | Randy Kelley | Sound Effects Editor |
| Sound | Glenn T. Morgan | Sound Effects Editor |
| Sound | Peter J. Lehman | Sound Effects Editor |
| Sound | Brian McPherson | Sound Effects Editor |
| Sound | Michael D. Wilhoit | Sound Effects Editor |
| Sound | Larry Kemp | Sound Effects Editor |
| Crew | Eric Chambers | Stunts |
| Art | David Lowery | Production Illustrator |
| Production | Linda Antipala | Casting |
| Production | Judith Bouley | Location Casting |
| Production | Randi Hiller | Casting Assistant |
| Production | Jimmy Jue | Extras Casting |
| Crew | Keith Tellez | Stunt Double |
| Crew | Steve Kelso | Stunt Double |
| Crew | Steve Kelso | Stunt Driver |
| Crew | Lynn Salvatori | Stunt Double |
| Production | Maria Norman | Executive Assistant |
