The big bad cats are the villains/Indians, and the little mice are the settlers going west in their little covered wagons, and the Indians are on a rampage about it. Things look dark indeed for the settlers when the likes of Buffalo Bill, General Custer and Daniel Boone are unable to defeat the attacking cats but...wait...up in the sky...here comes the singing, flying mouse...Mighty Mouse. Not recommended for Revisionists.
| Directing | Eddie Donnelly | Director |
| Production | Paul Terry | Producer |
| Writing | John Foster | Story |
| Sound | Philip A. Scheib | Music |