While searching for the man who framed him for a crime he didn't commit, Harrison Destry (John Gavin) stumbles into a town where an old cell mate of his is being tried for robbery and murder. The outlaw has hidden the loot and offers to reveal the location to Destry, but instead provides the location to Patience Dailey, a gold digging saloon singer played by Tammy Grimes.
| Directing | Don Siegel | Director |
| Writing | Robert Guy Barrows | Writer |
| Writing | Max Brand | Writer |
| Production | Howard Browne | Producer |
| Production | Carter DeHaven | Associate Producer |
| Sound | Morton Stevens | Sound |
| Camera | Lionel Lindon | Director of Photography |
| Editing | Richard M. Sprague | Editor |
| Art | Raymond Beal | Art Direction |
| Art | John McCarthy Jr. | Set Decoration |
| Art | Ralph Sylos | Set Decoration |
| Costume & Make-Up | Jack Barron | Makeup Artist |
| Costume & Make-Up | Florence Bush | Hairstylist |
| Directing | Ray Taylor Jr. | Assistant Director |
| Sound | Lyle Cain | Sound |
| Crew | Jesse Wayne | Stunts |
| Crew | Al Wyatt Sr. | Stunts |
| Costume & Make-Up | Vincent Dee | Costume Supervisor |
| Visual Effects | Robert Brower | Color Designer |
| Editing | David J. O'Connell | Editorial Coordinator |
| Sound | The Ledbetters | Theme Song Performance |
| Sound | Randy Sparks | Sound |
| Sound | Stanley Wilson | Sound |