Based on the journals of Che Guevara, leader of the Cuban Revolution. In his memoirs, Guevara recounts adventures he and best friend Alberto Granado had while crossing South America by motorcycle in the early 1950s.
| Camera | Éric Gautier | Director of Photography |
| Costume & Make-Up | Beatriz De Benedetto | Costume Design |
| Writing | Jose Rivera | Screenplay |
| Sound | Gustavo Santaolalla | Original Music Composer |
| Art | Carlos Conti | Production Design |
| Editing | Daniel Rezende | Editor |
| Costume & Make-Up | Marisa Urruti | Costume Design |
| Production | Walter Rippell | Casting |
| Directing | Walter Salles | Director |
| Production | Edgard Tenenbaum | Producer |
| Production | Karen Tenkhoff | Producer |
| Camera | Paula Prandini | Still Photographer |
| Lighting | Sergio Scalisi | Gaffer |
| Camera | Constanza Ott | First Assistant Camera |
| Crew | Fernando Ariel Menghi | Stunts |
| Sound | Dennis Twitty | Foley Editor |
| Art | Jorge Mondello | Property Master |
| Art | Ana Piaggio | Graphic Designer |
| Art | Martín Libert | Property Master |
| Art | Silvina Carballo | Assistant Production Design |
| Art | Matías Martínez | Assistant Production Design |
| Art | Alejandro Gastón Mondello | Assistant Property Master |
| Art | Ariel Guillermo Mondello | Assistant Property Master |
| Art | Julio Ojeda | Assistant Property Master |
| Art | Estella Zeballos | Assistant Property Master |
| Directing | Federico Berón | Second Assistant Director |
| Directing | Márcia Faria | First Assistant Director |
| Directing | Julia Solomonoff | First Assistant Director |
| Editing | Miguel Schverdfinger | Assistant Editor |
| Writing | Che Guevara | Novel |
| Production | Diego Dubcovsky | Producer |
| Production | Daniel Burman | Producer |
