Myron Breckinridge flies to Europe to get a sex-change operation and is transformed into the beautiful Myra. She travels to Hollywood, meets up with her rich Uncle Buck and, claiming to be Myron's widow, demands money. Instead, Buck gives Myra a job in his acting school. There, Myra meets aspiring actor Rusty and his girlfriend, Mary Ann. With Myra as catalyst, the trio begin to outrageously expand their sexual horizons.
| Directing | Michael Sarne | Director |
| Writing | Michael Sarne | Screenplay |
| Production | Robert Fryer | Producer |
| Writing | David Giler | Screenplay |
| Writing | Gore Vidal | Novel |
| Production | David Giler | Producer |
| Production | James Cresson | Associate Producer |
| Camera | Richard Moore | Director of Photography |
| Editing | Danford B. Greene | Editor |
| Art | Fred Harpman | Art Direction |
| Art | Jack Martin Smith | Art Direction |
| Art | Reg Allen | Set Decoration |
| Art | Walter M. Scott | Set Decoration |
| Costume & Make-Up | Theadora Van Runkle | Costume Design |
| Costume & Make-Up | Del Acevedo | Makeup Artist |
| Costume & Make-Up | Edith Lindon | Hairstylist |
| Costume & Make-Up | Daniel C. Striepeke | Makeup Supervisor |
| Production | William Eckhardt | Unit Production Manager |
| Directing | Richard Glassman | Assistant Director |
| Art | Greg C. Jensen | Construction Coordinator |
| Art | Rick Simpson | Leadman |
| Sound | Don J. Bassman | Sound |
| Sound | David Dockendorf | Sound |
| Sound | Terrance Emerson | Sound |
| Visual Effects | L.B. Abbott | Visual Effects |
| Visual Effects | Art Cruickshank | Visual Effects |
| Crew | Donna Garrett | Stunts |
| Crew | Russ McCubbin | Stunts |
| Camera | Thomas Del Ruth | Assistant Camera |
| Production | Michael McLean | Casting Consultant |
| Costume & Make-Up | Edith Head | Costumer |
| Editing | Hugh K. Cummings | Co-Editor |
| Crew | Chris Haynes | Driver |
| Crew | Ralph Beaumont | Choreographer |
| Crew | Don Prince | Unit Publicist |
| Crew | Marty Feldman | Script |
