A look at the lives of the strong-willed women of the Weston family, whose paths have diverged until a family crisis brings them back to the Midwest house they grew up in, and to the dysfunctional woman who raised them.
| Directing | John Wells | Director |
| Writing | Tracy Letts | Screenplay |
| Production | George Clooney | Producer |
| Production | Jean Doumanian | Producer |
| Production | Grant Heslov | Producer |
| Production | Steve Traxler | Producer |
| Sound | Gustavo Santaolalla | Original Music Composer |
| Editing | Stephen Mirrione | Editor |
| Art | David Gropman | Production Design |
| Art | Nancy Haigh | Set Decoration |
| Costume & Make-Up | Cindy Evans | Costume Design |
| Art | Karen Schulz Gropman | Art Direction |
| Art | Toni Marlo | Set Decoration |
| Costume & Make-Up | Jean Ann Black | Makeup Artist |
| Costume & Make-Up | Roxane Griffin | Key Hair Stylist |
| Costume & Make-Up | J. Roy Helland | Makeup Designer |
| Costume & Make-Up | Matthew W. Mungle | Makeup Artist |
| Costume & Make-Up | Björn Rehbein | Key Makeup Artist |
| Sound | Lon Bender | Sound Designer |
| Sound | Bill R. Dean | Sound Editor |
| Sound | Kris Fenske | Sound Editor |
| Sound | Marc Fishman | Sound Re-Recording Mixer |
| Sound | Glynna Grimala | Sound Editor |
| Sound | Tony Lamberti | Sound Re-Recording Mixer |
| Sound | Nancy MacLeod | Sound Editor |
| Sound | Dave McMoyler | Sound Editor |
| Sound | Christian P. Minkler | Sound Re-Recording Mixer |
| Sound | Mike Prestwood Smith | Sound Re-Recording Mixer |
| Sound | Daniel J. Leahy | Sound Re-Recording Mixer |
| Directing | Ian Calip | Second Assistant Director |
| Production | Bob Weinstein | Executive Producer |
| Art | Sean P. Egan | Art Department Coordinator |
| Writing | Tracy Letts | Theatre Play |
| Crew | Julie Michaels | Stunts |
| Crew | Caryn Mower | Stunts |
| Camera | Adriano Goldman | Director of Photography |
| Crew | Jon Bielich | Stunt Coordinator |
| Crew | Ted Barba | Stunt Double |
| Crew | Laurie Cummings | Stunts |
| Crew | Peewee Piemonte | Stunt Coordinator |
| Crew | Tabby Hanson | Stunts |
| Crew | Kent Shelton | Stunts |
| Crew | Jeff Burleson | Stunt Driver |
| Production | Deb Dyer | Unit Production Manager |
| Production | Harvey Weinstein | Executive Producer |
| Production | Kerry Barden | Casting |
| Production | Paul Schnee | Casting |
| Production | Ron Burkle | Executive Producer |
| Production | Celia D. Costas | Executive Producer |
| Production | Patrick Daly | Producer |
| Production | Ben Famigliett | Executive Producer |
| Production | Jerry Frankel | Executive Producer |
| Production | Arny Granat | Executive Producer |
| Production | Claire Rudnick Polstein | Executive Producer |
| Production | Jeffrey Richards | Executive Producer |
| Costume & Make-Up | Matthew W. Mungle | Prosthetic Makeup Artist |
| Costume & Make-Up | Lyndell Quiyou | Hairstylist |
| Crew | Jordan Roby | Stand In |
