"Weird Al" Yankovic guides the audience through a 3-D lesson on the human brain. Al answers "man on the street" questions, provides interesting trivia, and even recounts the unfortunate mishap of Phineaus Cage. The film ends with "The Brain Song," which details exactly how the brain works.
| Writing | 'Weird Al' Yankovic | Screenplay |
| Sound | Jim West | Music |
| Directing | 'Weird Al' Yankovic | Director |
| Camera | Peter Anderson | Director of Photography |