New York City, 1957. Lionel Essrog, a private detective living with Tourette syndrome, tries to solve the murder of his mentor and best friend, armed only with vague clues and the strength of his obsessive mind.
| Writing | Jonathan Lethem | Novel |
| Writing | Edward Norton | Screenplay |
| Directing | Edward Norton | Director |
| Production | Michael Bederman | Producer |
| Production | Bill Migliore | Producer |
| Production | Edward Norton | Producer |
| Production | Gigi Pritzker | Producer |
| Production | Rachel Shane | Producer |
| Sound | Daniel Pemberton | Original Music Composer |
| Camera | Dick Pope | Director of Photography |
| Editing | Joe Klotz | Editor |
| Art | Beth Mickle | Production Design |
| Art | Michael Ahern | Art Direction |
| Art | Kara Zeigon | Set Decoration |
| Production | Robert F. Smith | Executive Producer |
| Production | Daniel Nadler | Executive Producer |
| Production | Adrian Alperovich | Executive Producer |
| Production | Sue Kroll | Executive Producer |
| Production | Brian Niranjan Sheth | Executive Producer |
| Costume & Make-Up | Amy Roth | Costume Designer |
| Visual Effects | Mark Russell | Visual Effects Supervisor |
| Sound | Linda Cohen | Music Supervisor |
| Sound | Thom Yorke | Songs |
| Production | Avy Kaufman | Casting |
| Production | Michael Bederman | Unit Production Manager |
| Directing | Adam Escott | First Assistant Director |
| Directing | Nick Vanderpool | Second Assistant Director |
| Crew | Stephen A. Pope | Stunt Coordinator |
| Crew | G. A. Aguilar | Stunt Coordinator |
| Production | Silvana Tropea | Associate Producer |
| Production | Richard Keeshan | Production Supervisor |
| Sound | Paul Hsu | Sound Re-Recording Mixer |
| Art | Dan-ah Kim | Graphic Designer |
| Art | Sandy Hamilton | Property Master |
| Directing | Deirdre Horgan | Script Supervisor |
| Camera | Glen Wilson | Still Photographer |
| Sound | Danny Michael | Sound Mixer |
| Costume & Make-Up | Kerrie Smith | Hair Department Head |
| Lighting | William Newell | Gaffer |
| Camera | David Stern | Key Grip |
| Crew | Caleb P. Johnson | Special Effects Coordinator |
| Directing | G. A. Aguilar | Second Unit Director |
| Crew | Stuart Macphee | Post Production Supervisor |
| Visual Effects | Sophie-Ann Price | Visual Effects Coordinator |
| Sound | Paul Hsu | Supervising Sound Editor |
| Sound | Marko Costanzo | Foley Artist |
| Sound | Wynton Marsalis | Musician |
| Crew | Mark Fichera | Stunts |
| Crew | Ben Rezendes | Stunts |
| Crew | Josh Lakatos | Stunt Driver |
| Crew | Jim Ford | Stunts |
| Crew | Tim Gallin | Stunts |
| Crew | Christopher Jon Gombos | Stunts |
| Crew | Danny Schoch | Stunts |
| Crew | Bob Roseman | Stunts |
| Crew | Jodi Michelle Pynn | Stunts |
| Crew | Luis Moco | Stunts |
| Crew | Keil Oakley Zepernick | Stunts |
| Crew | William Cote | Stunts |
| Crew | Anthony Mecca | Stunts |
| Crew | Bobby Beckles | Stunt Driver |
| Crew | Blaise Corrigan | Stunt Driver |
| Crew | Peter Epstein | Stunt Driver |
| Crew | Thomas Place | Stunt Driver |
| Crew | Ashley Pynn | Stunt Driver |
| Crew | Jeremy Sample | Stunt Driver |
| Crew | Matt Triplett | Stunt Driver |
| Art | Hinju Kim | Assistant Art Director |
| Art | Daniel R. Kersting | Assistant Set Decoration |
| Art | Joanna Tillman | Set Decoration Buyer |
| Art | Kelly Solomon | Art Department Coordinator |
| Art | Cassandra Holden | Art Department Assistant |
| Art | Cara Gelbard | Art Department Assistant |
| Art | Emilie Misset | Art Department Assistant |
| Art | Ray Fisher | Leadman |
| Art | Mike Drury | Assistant Property Master |
| Art | Daniel Boxer | Props |
| Crew | Tommy Janulis | Picture Car Coordinator |
| Art | Jessie Curran | Props |
| Art | James Domorski | Set Dresser |
| Art | Katherine Vranesich | Set Dresser |
| Art | Danny Baeza | Set Dresser |
| Art | Jessica LeNoble | Set Dresser |
| Art | Jenna Shaffer | Set Dresser |
| Art | Jason Duncan | Set Dresser |
| Art | Ross Huttick | Set Dresser |
| Art | Andrew Burgh | Set Dresser |
| Art | Richard Liebgold | Set Dresser |
| Art | Angie Lenge | Set Dresser |
| Art | Valerie Scoppa-Misarti | Set Dresser |
| Art | Max Rarrick | Set Dresser |
| Art | Dan Krause | Set Dresser |
| Art | Roland Misarti | Set Dresser |
| Art | Curtis Oliveira | Set Dresser |
| Art | Jason Frair | Set Dresser |
| Art | Leon Seepersaud | Set Dresser |
| Camera | Craig Haagensen | "A" Camera Operator |
| Camera | Dick Pope | "B" Camera Operator |
| Camera | Sean P. Gilbert | Underwater Camera |
| Camera | Eric Swanek | First Assistant "A" Camera |
| Camera | Bobby Mancuso | First Assistant "B" Camera |
| Camera | Michael Guthrie | Second Assistant "A" Camera |
| Camera | Justin Mancuso | Second Assistant "B" Camera |
| Camera | Patrick Cecilian | Digital Imaging Technician |
| Camera | Chris Charmel | Camera Loader |
| Sound | Kira Smith | Boom Operator |
| Costume & Make-Up | Erika Goyzueta | Wardrobe Supervisor |
| Costume & Make-Up | Linda Giammarese | Wardrobe Supervisor |
| Costume & Make-Up | Caroline Horton | Key Costumer |
| Costume & Make-Up | Emmanuelle Martin | Costume Coordinator |
| Costume & Make-Up | Iris Horta Lemos | Set Costumer |
| Costume & Make-Up | James Massenburg | Set Costumer |
| Costume & Make-Up | Heather Howard | Set Costumer |
| Costume & Make-Up | Rene Marie Irwin | Set Costumer |
| Costume & Make-Up | Emily Nadeau | Set Costumer |
| Costume & Make-Up | Rosi Zingales | Tailor |
| Costume & Make-Up | John Quaglia | Key Hair Stylist |
| Costume & Make-Up | Betsy Reyes | Hairstylist |
| Costume & Make-Up | Jill McKay | Makeup Artist |
| Costume & Make-Up | Vincent Schicchi | Special Effects Makeup Artist |
| Lighting | Jonathan Stern | Best Boy Electric |
| Lighting | Patrick Wade | Rigging Gaffer |
| Camera | Michael Mervilde | Best Boy Grip |
| Camera | Chris DesRochers | Dolly Grip |
| Camera | Mike Morini | Dolly Grip |
| Camera | Dave Palestine | Grip |
| Camera | John Edison Blagg | Grip |
| Camera | Leo Schott | Grip |
| Camera | James Casey | Grip |
| Camera | Christopher F. Graneto | Grip |
| Lighting | Alan Blagg | Key Rigging Grip |
| Production | Mike Brant | Production Coordinator |
| Production | Shanae Rivers | Assistant Production Coordinator |
| Production | Kyle Fletcher | Production Secretary |
| Production | Drew Schofer | Location Manager |
| Production | Bill Ahern | Assistant Location Manager |
| Production | Jessi Partridge | Location Coordinator |
| Production | Terrell J. Merrill | Location Assistant |
| Production | Ali A. Rashti | Location Assistant |
| Production | Tremaine Renee | Location Assistant |
| Production | Emmanuel Sebastian | Location Assistant |
| Production | Tahnee Tangherlini | Location Assistant |
| Crew | Maurier Winston | Security |
| Production | Sean Hogan | Production Accountant |
| Production | Ann Caprio | First Assistant Accountant |
| Production | Matt Dunn | Second Assistant Accountant |
| Production | Logan Wasley | Payroll Accountant |
| Crew | Casey Bader | Actor's Assistant |
| Crew | Karen C. Eide | Actor's Assistant |
| Production | Chase Sund | Producer's Assistant |
| Production | Emily Kob | Producer's Assistant |
| Production | Chloe Eichler | Producer's Assistant |
| Production | Mariah Gregory | Producer's Assistant |
| Production | Chelsea Bradshaw | Producer's Assistant |
| Art | Gary Grill | Construction Coordinator |
| Crew | John Hicks | Transportation Captain |
| Crew | Wayne Anderson | Driver |
| Crew | Joe Gonzales | Driver |
| Crew | Donald Bowers | Driver |
| Crew | P. Louis Jean | Driver |
| Crew | Kahlil Bess | Driver |
| Crew | Zhivago Jones | Driver |
| Crew | Kenny Brown | Driver |
| Crew | David Labutte | Driver |
| Crew | Arlen Cadle | Driver |
| Crew | John Long | Driver |
| Crew | Luis Falquez | Driver |
| Crew | Scott McGraw | Driver |
| Crew | Eric Fritsch | Driver |
| Crew | Daniel Petretti | Driver |
| Crew | Mike Pezzalla | Driver |
| Crew | Dimitri Giannios | Driver |
| Crew | Joe Salters | Driver |
| Crew | John Giordano | Driver |
| Crew | Joe Schultz | Driver |
| Crew | Mike Sangiamo | Driver |
| Directing | Tom Glick | Second Second Assistant Director |
| Production | Leeba Zakharov | Casting Associate |
| Production | Grant Wilfley | Background Casting Director |
| Production | Scotty Anderson | Casting Assistant |
| Crew | Julie Kuehndorf | Unit Publicist |
| Camera | Anastas N. Michos | Second Unit Director of Photography |
| Camera | Jack Donnelly | Second Unit Director of Photography |
| Production | Annie Gaudet | Post Production Accountant |
| Sound | Craig Kyllonen | Assistant Sound Editor |
| Sound | Marissa Littlefield | Sound Editor |
| Sound | Philip Stockton | Sound Editor |
| Sound | Nicholas Schenck | Sound Editor |
| Sound | Allan Zaleski | Sound Editor |
| Sound | George A. Lara | Foley Recording Engineer |
| Production | Dann Fink | ADR Voice Casting |
| Production | Bruce Winant | ADR Voice Casting |
| Visual Effects | John Bair | Visual Effects Supervisor |
| Visual Effects | Eran Dinur | Visual Effects Supervisor |
| Visual Effects | Stevie Ramone | Visual Effects Supervisor |
| Visual Effects | Osvaldo Andreaus | Visual Effects Supervisor |
| Visual Effects | David Lebensfeld | Visual Effects Supervisor |
| Sound | Katherine Gordon Miller | Music Editor |
| Costume & Make-Up | Louise McCarthy | Makeup Department Head |
| Visual Effects | Kenzi Parker | Digital Compositor |
| Crew | Aaron Vexler | Stunts |
