In 1561, Mary Stuart, widow of the King of France, returns to Scotland, reclaims her rightful throne and menaces the future of Queen Elizabeth I as ruler of England, because she has a legitimate claim to the English throne. Betrayals, rebellions, conspiracies and their own life choices imperil both Queens. They experience the bitter cost of power, until their tragic fate is finally fulfilled.
| Directing | Josie Rourke | Director |
| Camera | John Mathieson | Director of Photography |
| Writing | Beau Willimon | Screenplay |
| Editing | Chris Dickens | Editor |
| Art | James Merifield | Production Design |
| Costume & Make-Up | Alexandra Byrne | Costume Design |
| Writing | John Guy | Book |
| Sound | Max Richter | Original Music Composer |
| Production | Tim Bevan | Producer |
| Production | Eric Fellner | Producer |
| Production | Debra Hayward | Producer |
| Production | Jane Robertson | Co-Producer |
| Art | Gina Cromwell | Set Decoration |
| Production | Richard May | Production Manager |
| Directing | Alex Oakley | First Assistant Director |
| Sound | Ian Wilson | Supervising Sound Editor |
| Sound | Alastair Sirkett | Sound Mixer |
| Crew | Mark Flanagan | Stunts |
| Costume & Make-Up | Jenny Shircore | Makeup Designer |
| Costume & Make-Up | Marc Pilcher | Hairstylist |
| Costume & Make-Up | Jessica Brooks | Makeup Artist |
| Sound | Kirsten Lane | Music Consultant |
| Crew | Peter Dillon | Stunts |
| Production | Amelia Granger | Executive Producer |
| Production | Liza Chasin | Executive Producer |
| Production | Kate Pakenham | Executive Producer |
| Costume & Make-Up | Jenny Shircore | Hair Designer |
| Production | Alastair Coomer | Casting Director |
| Crew | Alex Beckett | In Memory Of |
| Crew | Russell Balogh | Stunts |
| Crew | Tony Condren | Stunt Coordinator |
| Crew | Richard Ryan | Stunt Coordinator |
| Crew | Jason Beeston | Stunts |
| Crew | Adam Behan | Stunts |
| Crew | Gerry Behan | Stunts |
| Crew | James Bewley | Stunts |
| Crew | Sean Bingham | Stunts |
| Crew | Lemuel Black | Stunts |
| Crew | Dave Boyle | Stunts |
| Crew | Aran Condren | Stunts |
| Crew | Sean Condren | Stunts |
| Crew | Max Cormac | Stunts |
| Crew | James Cosgrave | Stunts |
| Crew | Darren Costello | Stunts |
| Crew | Gavin Coventry | Stunts |
| Crew | Ken Doherty | Stunts |
| Crew | Shay Doherty | Stunts |
| Crew | Levan Doran | Stunts |
| Crew | Stav Dvorkin | Stunts |
| Crew | Jonathan East | Stunts |
| Crew | Stuart Frift | Stunts |
| Crew | David Garrick | Stunts |
| Crew | Michael Hanna | Stunts |
| Crew | Richard Leggett | Stunts |
| Crew | Edward Linard | Stunts |
| Crew | Jinny Lofthouse | Stunts |
| Crew | Nathaniel Marten | Stunts |
| Crew | Mathew McKay | Stunts |
| Crew | Erol Mehmet | Stunts |
| Crew | Jack Miles | Stunts |
| Crew | Ciaran O'Grady | Stunts |
| Crew | Alex Payne | Stunts |
| Crew | Justin Pearson | Stunts |
| Crew | Andy Pilgrim | Stunts |
| Crew | Dan Styles | Stunts |
| Crew | Harvey Taylor | Stunts |
| Crew | Richie Wilson | Stunts |
| Crew | Lauterio Zamparelli | Stunts |
| Production | Harriet Spencer | Associate Producer |
| Directing | James Manning | Second Assistant Director |
| Crew | Tania Blunden | Post Production Supervisor |
| Production | Angela Moneke | Production Coordinator |
| Camera | Pete Cavaciuti | "A" Camera Operator |
| Camera | Pete Cavaciuti | Steadicam Operator |
| Camera | Simon Hume | First Assistant "A" Camera |
| Camera | Simon Dunn | Second Assistant "A" Camera |
| Camera | Rodrigo Gutierrez | "B" Camera Operator |
| Camera | Lewis Hume | First Assistant "B" Camera |
| Camera | Archie Muller | Second Assistant "B" Camera |
| Camera | Angus Hudson | "C" Camera Operator |
| Camera | Angus Hudson | Second Unit Director of Photography |
| Camera | Keith McNamara | First Assistant "C" Camera |
| Camera | Calem Trevor | Second Assistant "C" Camera |
| Camera | Derek Walker | "D" Camera Operator |
| Camera | Tommy Holman | First Assistant "D" Camera |
| Camera | Kat Spencer | Second Assistant "D" Camera |
| Camera | Filippo Maso | Camera Trainee |
| Camera | Nick Poole | Camera Trainee |
| Camera | Dafydd Bates | Camera Trainee |
| Camera | Laura Sulca | Camera Trainee |
| Camera | Alex Golding | Digital Imaging Technician |
| Camera | Anthony Dias | Digital Imaging Technician |
| Directing | Lucy Ward | Script Supervisor |
| Sound | Robert Flanagan | Production Sound Mixer |
| Sound | Paul Naughton | Boom Operator |
| Art | James Wakefield | Supervising Art Director |
| Art | Todd Ellis | Standby Art Director |
| Art | Toby Britton | Art Direction |
| Art | Gavin Fitch | Art Direction |
| Art | Oliver Goodier | Art Direction |
| Art | Gavin Dean | Assistant Art Director |
| Art | Isona Rigau | Assistant Art Director |
| Art | Matthew Robinson | Assistant Art Director |
| Art | Denise Ball | Draughtsman |
| Art | Catherine Whiting | Draughtsman |
| Art | Lotta Wolgers | Draughtsman |
| Art | Tom Turner | Draughtsman |
| Art | Andrew Tilhoo | Draughtsman |
| Art | Jenny Hawes | Art Department Coordinator |
| Art | Tamara Catlin-Birch | Art Department Coordinator |
| Art | Marie Boon | Art Department Assistant |
| Art | Ava Skeet | Art Department Assistant |
| Art | Emma MacDevitt | Assistant Set Decoration |
| Art | Samantha Redwood | Assistant Set Decoration |
| Art | Finlay Britton | Storyboard Artist |
| Costume & Make-Up | Brendan Handscombe | Costume Supervisor |
| Costume & Make-Up | Laura Smith | Assistant Costume Designer |
| Costume & Make-Up | Kate Chadderton | Costume Coordinator |
| Costume & Make-Up | Sarah Brest | Wardrobe Master |
| Costume & Make-Up | Sarah Kelly | Key Hair Stylist |
| Costume & Make-Up | Sarah Kelly | Key Makeup Artist |
| Costume & Make-Up | Hannah Edwards | Key Hair Stylist |
| Costume & Make-Up | Hannah Edwards | Key Makeup Artist |
| Costume & Make-Up | Louise Coles | Makeup & Hair |
| Costume & Make-Up | Annette Field | Makeup & Hair |
| Costume & Make-Up | Susie Redfern | Makeup & Hair |
| Costume & Make-Up | Karen Teitge | Makeup & Hair |
| Costume & Make-Up | Matt George | Wigmaker |
| Costume & Make-Up | Alex Rouse | Wigmaker |
| Costume & Make-Up | Terry Jarvis | Wigmaker |
| Production | Pat Karam | Location Manager |
| Production | Mark Walledge | Location Manager |
| Production | Andrew Ryland | Location Manager |
| Production | Ian Hutchinson | Location Manager |
| Production | Chris Johnston | Location Manager |
| Production | Nathan Flaher | Assistant Location Manager |
| Production | Ian Lumsden | Assistant Location Manager |
| Production | Karl King | Unit Manager |
| Editing | Debs Richardson | First Assistant Editor |
| Crew | Andy Hague | Visual Effects Editor |
| Crew | Heidi Freeman | Visual Effects Editor |
| Editing | Nina Annan | Assistant Editor |
| Editing | Victoria Blackwood | Assistant Editor |
| Editing | Paolo Magni | Assistant Editor |
| Production | Alice Syed | Production Coordinator |
| Production | Imogen Turner | Assistant Production Coordinator |
| Production | Sarah Cook | Production Secretary |
| Lighting | Alan Martin | Gaffer |
| Camera | David Appleby | Key Grip |
| Camera | Jim Crowther | Best Boy Grip |
| Camera | Gary Romaine | Grip |
| Camera | Craig Shiels | Grip |
| Visual Effects | Neal Champion | Special Effects Supervisor |
| Production | Isabella Odoffin | Casting Associate |
| Production | Eliza Heslop | Casting Assistant |
| Camera | Liam Daniel | Still Photographer |
| Crew | Wendy Kidd | Unit Publicist |
| Crew | Dean Thomas | Transportation Captain |
| Sound | Ian Wilson | Sound Designer |
| Sound | Steve Single | Dialogue Editor |
| Sound | Adele Fletcher | ADR Editor |
| Sound | Alastair Sirkett | Sound Designer |
| Sound | Hugo Adams | Foley Supervisor |
| Sound | Lilly Blazewicz | Foley Editor |
| Sound | Glen Gathard | Foley Mixer |
| Sound | Peter Burgis | Foley Artist |
| Sound | Zoe Freed | Foley Artist |
| Sound | Sue Harding | Foley Artist |
| Sound | Steve Single | Sound Re-Recording Mixer |
| Sound | Andrew Caller | Sound Re-Recording Mixer |
| Sound | Michael Connell | Music Editor |
| Sound | Dave Foster | Orchestrator |
| Sound | Max Richter | Orchestrator |
| Directing | Alicia Brockenbrow | Assistant Director |
