A shy comic book fan is injected with an experimental serum and starts turning into a spider. When web covered bodies start appearing a policeman starts to investigate the strange case.
| Directing | Scott Ziehl | Director |
| Writing | Cary Solomon | Writer |
| Production | Lou Arkoff | Producer |
| Visual Effects | Dan Schmit | Special Effects Supervisor |
| Costume & Make-Up | Julia Schklair | Costume Design |
| Writing | Mark 'Crash' McCreery | Story |
| Camera | Thomas L. Callaway | Director of Photography |
| Art | Peter Borck | Art Direction |
| Production | Shari Steinberg | Casting Associate |
| Costume & Make-Up | Hayley Stuppel | Set Costumer |
| Visual Effects | John K. Jenkins | Visual Effects Supervisor |
| Sound | Takako Ishikawa | Sound Effects Editor |
| Production | Stan Winston | Producer |
| Sound | Bob Arons | Sound Effects Editor |
| Visual Effects | Shane Mahan | Special Effects Supervisor |
| Writing | Chuck Konzelman | Writer |
| Writing | Max Enscoe | Writer |
| Production | Colleen Camp | Producer |
| Sound | Jonathan Golodner | Sound Effects Editor |
| Camera | Paul Janossy | First Assistant Camera |
| Writing | Chuck Konzelman | Story |
| Writing | Annie DeYoung | Writer |
| Directing | Samantha C. Kirkeby | Script Supervisor |
| Camera | Chuck Zlotnick | Still Photographer |
| Costume & Make-Up | Kathy Kane-Macgowan | Key Hair Stylist |
| Writing | Cary Solomon | Story |
| Camera | Ken Blakey | Camera Operator |
| Costume & Make-Up | Myke Michaels | Makeup Department Head |
| Costume & Make-Up | Stephanie Coffey | Makeup Artist |
| Costume & Make-Up | Mandi Line | Assistant Costume Designer |
| Sound | David Reynolds | Music |
| Costume & Make-Up | Michael Ornelaz | Key Hair Stylist |
| Sound | Robert Nichols II | Sound Recordist |