Portland, Oregon, 1971. Bob Hughes is the charismatic leader of a peculiar quartet, formed by his wife, Dianne, and another couple, Rick and Nadine, who skillfully steal from drugstores and hospital medicine cabinets in order to appease their insatiable need for drugs. But neither fun nor luck last forever.
You can now watch Drugstore Cowboy online on the following streaming providers in the United States.
| Directing | Gus Van Sant | Director |
| Production | Karen Murphy | Producer |
| Production | Nick Wechsler | Producer |
| Writing | Gus Van Sant | Screenplay |
| Writing | Daniel Yost | Screenplay |
| Production | Cary Brokaw | Executive Producer |
| Camera | Robert D. Yeoman | Director of Photography |
| Editing | Mary Bauer | Editor |
| Production | Sharon Bialy | Casting |
| Production | Richard Pagano | Casting |
| Art | David Brisbin | Production Design |
| Art | Eve Cauley | Art Direction |
| Art | Margaret Goldsmith | Set Decoration |
| Sound | Elliot Goldenthal | Original Music Composer |
| Production | Karen Koch | Production Manager |
| Directing | David B. Householter | First Assistant Director |
| Directing | Robin Leigh Fleck | Second Assistant Director |
| Production | Laurie Parker | Production Executive |
| Production | Claudia Lewis | Production Executive |
| Production | Eric McLeod | Production Coordinator |
| Production | Charles Harrington | Location Manager |
| Art | Missy Stewart | Set Dresser |
| Art | Michael Gastaldo | Property Master |
| Costume & Make-Up | Marsha Perloff | Wardrobe Supervisor |
| Costume & Make-Up | Lizbeth Williamson | Makeup Artist |
| Costume & Make-Up | Gina Monaci | Hair Designer |
| Camera | Eric Alan Edwards | Second Unit Director of Photography |
| Lighting | Chris Morley | Gaffer |
| Camera | Les Percy | Key Grip |
| Sound | Ron Judkins | Sound Mixer |
| Sound | Robert Jackson | Boom Operator |
| Directing | Jane Goldsmith | Script Supervisor |
| Crew | Leslie A. Leitner | Post Production Supervisor |
| Sound | Dane A. Davis | Supervising Sound Editor |
| Sound | John Kwiatkowski | Sound Effects Editor |
| Sound | Jerry Trent | Foley Artist |
| Sound | Joan Rowe | Foley Artist |
| Crew | David Boushey | Stunt Coordinator |
| Sound | Wayne Heitman | Sound Re-Recording Mixer |
| Sound | Matthew Iadarola | Sound Re-Recording Mixer |
| Sound | Mark 'Frito' Long | Sound Recordist |
| Sound | Joel Iwataki | Sound Engineer |
| Costume & Make-Up | Beatrix Aruna Pasztor | Costume Designer |
| Editing | Curtiss Clayton | Editor |
| Writing | James Fogle | Novel |
