After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.
| Production | Sarah Bradshaw | Associate Producer |
| Sound | Danny Elfman | Music |
| Camera | Guillermo Navarro | Director of Photography |
| Writing | Stephen Gaghan | Screenplay |
| Directing | Stephen Gaghan | Director |
| Crew | Stephen Gaghan | Script |
| Editing | Nick Moore | Editor |
| Editing | Craig Alpert | Editor |
| Directing | William M. Connor | First Assistant Director |
| Art | Gary Tomkins | Art Direction |
| Directing | Sandrine Loisy | Crowd Assistant Director |
| Costume & Make-Up | Jenny Beavan | Costume Design |
| Production | Joe Roth | Producer |
| Production | Lucy Bevan | Casting |
| Art | Dominic Watkins | Production Design |
| Production | Jeff Kirschenbaum | Producer |
| Production | Susan Downey | Producer |
| Camera | Julian Bucknall | First Assistant Camera |
| Art | Matthew Gray | Supervising Art Director |
| Sound | Chris Munro | Sound Mixer |
| Production | Jon Mone | Executive Producer |
| Directing | Simon Crane | Second Unit Director |
| Writing | Chris McKay | Screenplay |
| Art | Tom Whitehead | Art Direction |
| Art | Will Coubrough | Art Direction |
| Camera | Jay Maidment | Still Photographer |
| Art | Peter Dorme | Art Direction |
| Art | Tom Weaving | Art Direction |
| Costume & Make-Up | Zoe Tahir | Hairstylist |
| Writing | Hugh Lofting | Characters |
| Visual Effects | Hugh Lofting | Character Designer |
| Production | Emily Brockmann | Casting Associate |
| Production | Mark Layton | Production Supervisor |
| Costume & Make-Up | Joseph Koniak | Hair Setup |
| Production | Frank Cuomo | Production Manager |
| Production | Simone Goodridge | Unit Production Manager |
| Lighting | Ross Grimshaw | Lighting Technician |
| Costume & Make-Up | Chris Lyons | Special Effects Makeup Artist |
| Art | Tim Browning | Conceptual Design |
| Directing | Joey Coughlin | Second Assistant Director |
| Writing | David Allcock | Storyboard |
| Production | Duncan Broadfoot | Location Manager |
| Visual Effects | Bryce Nielsen | Visual Effects Producer |
| Directing | John Beckett | Script Supervisor |
| Art | Sebastian Lochmann | Concept Artist |
| Crew | James Bomalick | Stunts |
| Art | Oliver Roberts | Art Direction |
| Directing | Tom Rye | Second Assistant Director |
| Directing | Teresa Orlando | Third Assistant Director |
| Art | Alison Clements | Draughtsman |
| Crew | Darren Shearwood | Special Effects |
| Art | Martin Bell | Art Department Assistant |
| Camera | Alex Bender | Second Unit Director of Photography |
| Crew | Dew John | Transportation Captain |
| Art | Jimmy Rich | Assistant Set Dresser |
| Writing | Thomas Shepherd | Screenplay |
| Costume & Make-Up | Daniel Phillips | Makeup & Hair |
| Crew | Frank Cuomo | Post Production Supervisor |
| Production | Richard Ruck | Unit Manager |
| Directing | Mark Johnstone | Third Assistant Director |
| Directing | Marlon Beyer Rieger | Third Assistant Director |
