The film chronicles George's adventures as he befriends Kayla, a baby elephant, at a magic circus show and helps her travel across the country to be reunited with her family.Accompanied by his friend, the Man with the Yellow Hat, George travels by foot, train, and truck to reach Kayla's brother and sister in California, only to be accused of elephant-napping and brought all the way back to New York.
| Directing | Norton Virgien | Director |
| Art | Matt Williames | Art Department Manager |
| Production | Susan Blu | Casting |
| Editing | John Bryant | Editor |
| Sound | Heitor Pereira | Original Music Composer |
| Production | Jim Whitaker | Co-Executive Producer |
| Production | David Bernardi | Co-Executive Producer |
| Production | Ron Howard | Executive Producer |
| Production | Brian Grazer | Executive Producer |
| Production | David Kirschner | Executive Producer |
| Production | Jon Shapiro | Executive Producer |
| Production | Share Stallings | Producer |
| Writing | Chuck Tately | Story |
| Writing | Chuck Tately | Screenplay |
| Writing | Darrell Rooney | Story |
| Production | Leanne Moreau | Associate Producer |
| Art | Bob Kline | Art Direction |
| Writing | Andrei Svislotski | Head of Story |
| Production | David Vasquez | Production Coordinator |
| Sound | Slamm Andrews | Music Editor |
| Sound | Frederick Howard | Sound Supervisor |
| Sound | Elliott Koretz | Sound Effects Editor |
| Sound | Derek Pippert | Foley Supervisor |
| Sound | Jeff Rosen | Dialogue Editor |
