After he and his first wife separate, journalist David Sheff struggles to help their teenage son Nic, who goes from experimenting with drugs to becoming devastatingly addicted to methamphetamine.
| Directing | Felix Van Groeningen | Director |
| Writing | Luke Davies | Screenplay |
| Writing | Nic Sheff | Book |
| Production | Brad Pitt | Producer |
| Production | Dede Gardner | Producer |
| Production | Jeremy Kleiner | Producer |
| Production | Nan Morales | Executive Producer |
| Production | Francine Maisler | Casting |
| Art | Ethan Tobman | Production Design |
| Art | Patrick M. Sullivan Jr. | Art Direction |
| Art | Jennifer Lukehart | Set Decoration |
| Costume & Make-Up | Emma Potter | Costume Design |
| Costume & Make-Up | Jennifer Bell | Hairstylist |
| Costume & Make-Up | Kristen Kirchen | Hairstylist |
| Costume & Make-Up | Robert Mrazik | Hairstylist |
| Directing | George Bamber | First Assistant Director |
| Sound | Gabe Hilfer | Music Supervisor |
| Costume & Make-Up | Nancy Au | Costume Supervisor |
| Camera | Ruben Impens | Director of Photography |
| Crew | Rocky Capella | Stunts |
| Crew | Kelly Richardson | Stunts |
| Editing | Nico Leunen | Editor |
| Writing | Felix Van Groeningen | Screenplay |
| Writing | David Sheff | Book |
| Production | Sarah Esberg | Executive Producer |
