Larysa Rudenko
- Birthday: 1918-01-15
- Deathday: 1981-01-19
- Place of birth: Makiivka, Ukraine
- Also know as: Лариса Архипівна Руденко
Larysa Rudenko was a Ukrainian mezzo-soprano singer. She was a soloist at the Kyiv Opera between 1939-1970, and later taught music at the Kyiv Conservatorium.
