Yuuko Sasamoto
- Birthday: 1973-01-30
- Place of birth: Chiba, Japan
- Also know as: ささもと ゆうこ
Yuuko Sasamoto (笹本 優子, Sasamoto Yūko, January 30, 1973) is a Japanese voice actress from Chiba Prefecture. She is affiliated with Apte Pro. Previously she was affiliated with Arts Vision, Office Nozawa and Media Force.
