Pushed to the breaking-up point after their latest 'why can't you do this one little thing for me?' argument, Brooke calls it quits with her boyfriend Gary. What follows is a hilarious series of remedies, war tactics, overtures and undermining tricks – all encouraged by the former couple's friends and confidantes …and the occasional total stranger! When neither ex is willing to move out of their shared apartment, the only solution is to continue living as hostile roommates until one of them reaches breaking point.
| Editing | Dan Lebental | Editor |
| Production | Vince Vaughn | Producer |
| Writing | Jay Lavender | Story |
| Production | Stuart M. Besser | Executive Producer |
| Writing | Jeremy Garelick | Story |
| Writing | Jay Lavender | Screenplay |
| Production | Scott Stuber | Producer |
| Writing | Jeremy Garelick | Screenplay |
| Editing | David Rosenbloom | Editor |
| Directing | Peyton Reed | Director |
| Camera | Eric Alan Edwards | Director of Photography |
| Production | Peter Billingsley | Executive Producer |
| Writing | Vince Vaughn | Story |
| Production | Jeremy Garelick | Co-Producer |
| Production | Jay Lavender | Co-Producer |
| Production | John Isbell | Associate Producer |
| Production | Victoria Vaughn | Associate Producer |
| Production | Jeanne McCarthy | Casting |
| Sound | John O'Brien | Music Supervisor |
| Art | Andrew Laws | Production Design |
| Production | Juel Bestrop | Casting |
| Costume & Make-Up | Carol Oditz | Costume Design |
| Production | Stuart M. Besser | Unit Production Manager |
| Directing | Todd Amateau | First Assistant Director |
| Directing | Nina Jack | Second Assistant Director |
| Production | Mitchell E. Dauterive | Production Supervisor |
| Camera | Paul DeMarte | First Assistant "B" Camera |
| Camera | Melissa Moseley | Still Photographer |
| Costume & Make-Up | Nancy Cavallaro | Set Costumer |
| Production | Jaime Harlan | Casting Assistant |
| Editing | Gregory Plotkin | First Assistant Editor |
| Sound | Teri E. Dorman | Dialogue Editor |
| Sound | David Betancourt | Foley Mixer |
| Sound | John Pritchett | Production Sound Mixer |
| Art | Daniel B. Clancy | Set Decoration |
| Camera | Fred Folmer | Dolly Grip |
| Production | Al Nolan-Cohn | Location Manager |
| Costume & Make-Up | Ellen Ryba | Assistant Costume Designer |
| Crew | Darnell Jones | Transportation Co-Captain |
| Art | Paul Meylink | Storyboard Artist |
| Art | Scott Troha | Leadman |
| Production | Stacy Laiderman | Art Department Production Assistant |
| Camera | Jody Williams | "B" Camera Operator |
| Lighting | Dick Oakes | Gaffer |
| Costume & Make-Up | Thomas J. Glynn | On Set Dresser |
| Sound | Kimberly Harris | Supervising ADR Editor |
| Art | David Sandefur | Art Direction |
| Camera | Peter Rosenfeld | "A" Camera Operator |
| Lighting | James F. Roorda | Key Rigging Grip |
| Art | Maria C. Roxas | Location Scout |
| Production | Tracy Dixon | Extras Casting |
| Editing | Sandra Torres Granovsky | First Assistant Editor |
| Crew | Thaddeus E. Larkowski | Transportation Coordinator |
| Sound | Jon Michaels | First Assistant Sound Editor |
| Sound | Doc Kane | ADR Mixer |
| Sound | Steve Bartek | Conductor |
| Camera | Don Miller | Best Boy Grip |
| Camera | John Hudecek | Dolly Grip |
| Costume & Make-Up | Jacqueline S. Beatka | Set Costumer |
| Production | Lori Scowley | Production Accountant |
| Camera | Peter Rosenfeld | Steadicam Operator |
| Art | Marco Rubeo | Assistant Art Director |
| Camera | Peter Kuttner | First Assistant "A" Camera |
| Crew | John D. Milinac | Special Effects Coordinator |
| Costume & Make-Up | Gina Marie Ome | Key Costumer |
| Sound | Linda Folk | ADR Editor |
| Sound | David Williams | Dialogue Editor |
| Production | Patrick Muldoon | Assistant Location Manager |
| Costume & Make-Up | Annie Laoparadonchai | Costumer |
| Costume & Make-Up | Alyssa Kim | Costumer |
| Lighting | Chris Mulsoff | Rigging Gaffer |
| Production | Martha Lafage | Assistant Location Manager |
| Production | Barry Barclay | Production Coordinator |
| Crew | Sean T. Stratton | Post Production Supervisor |
| Crew | Michael P. Deal | Transportation Captain |
| Sound | Jason W. Jennings | Sound Effects Editor |
| Sound | Alicia Stevenson | Foley Artist |
| Production | Barbara Harris | ADR Voice Casting |
| Camera | Jody Williams | Second Unit Director of Photography |
| Crew | Lisa Gillespie | Cableman |
| Art | William D'Ambra | Property Master |
| Editing | Richmond Riedel | Assistant Editor |
| Sound | Ulrika Akander | Supervising Dialogue Editor |
| Sound | Kevin Warendorp | Assistant Sound Editor |
| Sound | Thomas J. O'Connell | ADR Mixer |
| Sound | Jeanette Browning | ADR Recordist |
| Sound | Steve Pederson | Sound Re-Recording Mixer |
| Production | Mickie Paskal | Local Casting |
| Sound | Cameron Frankley | Sound Designer |
| Sound | Rick Canelli | ADR Recordist |
| Sound | Dawn Fintor | Foley Artist |
| Crew | Joe Bucaro III | Stunt Coordinator |
| Camera | Greg Jackson | Second Assistant "B" Camera |
| Directing | Sheila Waldron | Script Supervisor |
| Camera | Art Bartels | Key Grip |
| Production | Elicia Zimmerman | Location Coordinator |
| Costume & Make-Up | Jane Blank | Seamstress |
| Editing | Gary Burritt | Negative Cutter |
| Art | Brian Cho | Art Department Coordinator |
| Camera | Joe Carpita | Camera Loader |
| Costume & Make-Up | Nina Hallworth | Costume Designer |
| Costume & Make-Up | Dominic Mango | Hair Department Head |
| Costume & Make-Up | Chris McMillan | Hairstylist |
| Production | Joseph Hicks | Extras Casting |
| Production | Ruth Goff | Extras Casting |
| Production | Paula Stier | Production Secretary |
| Art | Bruce DiValerio | Construction Coordinator |
| Sound | David M. Roberts | Boom Operator |
| Lighting | Robert Swander | Best Boy Electric |
| Sound | Scott Curtis | Foley Editor |
| Sound | Christopher Flick | Foley Editor |
| Art | Stephanie Gilliam | Set Designer |
| Camera | George Kohut | "B" Camera Operator |
| Costume & Make-Up | Claire Hallworth | Costume Designer |
| Costume & Make-Up | Joyce Kogut | Costume Supervisor |
| Costume & Make-Up | Tony Mirante | Assistant Hairstylist |
| Production | Jennifer Rudnicke | Local Casting |
| Production | Jonathan Kinnas | Extras Casting |
| Camera | Colin Slaby | Second Assistant "A" Camera |
| Costume & Make-Up | Suzi Ostos | Makeup Department Head |
| Production | Seth Yanklewitz | Casting Associate |
| Production | Andrew Blau | Production Coordinator |
| Sound | Cameron Frankley | Sound Supervisor |
| Sound | Steve Bartek | Orchestrator |
| Art | David J. Chamerski | Assistant Property Master |
| Directing | Anthony J. Nahar | Second Second Assistant Director |
| Costume & Make-Up | Terry Anderson | Assistant Costume Designer |
| Costume & Make-Up | Angela Levin | Makeup Artist |
| Sound | David V. Butler | Dialogue Editor |
| Sound | Randy Kelley | Sound Effects Editor |
| Sound | Ai-Ling Lee | Sound Effects Editor |
| Sound | Brad Sherman | Sound Re-Recording Mixer |
| Sound | Jonathan Karp | Music Editor |
| Sound | Jon Brion | Original Music Composer |
| Costume & Make-Up | Chelo Ontiveros | Key Makeup Artist |
| Costume & Make-Up | Clare Hallworth | Costume Design |
| Camera | Louisa McHugh | Camera Intern |
| Production | Mike Doto | Production Manager |
| Crew | Michael T. Brady | Stunts |
| Directing | Cara Giallanza | Assistant Director |
| Art | Matt Reitsma | Textile Artist |
| Editing | Stacey Frederick | Assistant Editor |
| Production | Cliff Zimowski | Additional Production Assistant |
| Sound | Dan Guachione | Boom Operator |
| Art | David E. Scott | Graphic Designer |
| Production | Nick Rafferty | Location Assistant |
| Sound | Jon Michaels | Assistant Sound Editor |
| Lighting | Jaime Dawkins | Rigging Grip |
| Editing | Olivia Giachino | Editorial Production Assistant |
| Crew | Marijan 'Mario' Zoric | Chef |
| Crew | Nathaniel E. Bell | Set Production Assistant |
| Production | Timber Kislan | Payroll Accountant |
| Production | Jennifer Webb | Travel Coordinator |
| Camera | E.J. Huntemann | Grip |
| Crew | Steve Hull | Carpenter |
| Art | Veloz Gomez | Set Dresser |
| Crew | Assata Amoaku | Craft Service |
| Lighting | Noah Banks | Lighting Technician |
| Crew | Ina Haybaeck-Rogers | Choreographer |
| Crew | Brigitte Bourque | Compositor |
| Crew | John J. Slove Jr. | Propmaker |
| Visual Effects | Heather Elisa Hill | Visual Effects Coordinator |
| Camera | Steven R. Wojcik | Additional Camera |
| Crew | John M. Pisani | Unit Publicist |
| Crew | Frank Battaglia | Special Effects Technician |
| Production | Alex Cohn | Location Manager |
| Production | Olivier Agostini | Production Assistant |
| Lighting | Chad Catuara | Electrician |
| Editing | Donnie Creighton | Digital Intermediate Assistant |
| Production | Frank Cuomo | Post Production Coordinator |
| Production | Abby Lorts | Location Production Assistant |
| Production | Jeremy Beiermann | Assistant Production Coordinator |
| Production | Lindsay Heller | Extras Casting Assistant |
| Costume & Make-Up | Lisa Jelic | Makeup Artist |
| Costume & Make-Up | Erika Walthall | Costume Assistant |
| Sound | Jay Duerr | Music Editor |
| Camera | Eric Wheeler | Assistant Camera |
| Art | Terry Baughman | Construction Foreman |
| Editing | Mike Kennedy | Digital Intermediate Producer |
| Production | Donald Fly | General Manager |
| Crew | Michael R. Cairo | Driver |
| Art | Kyle Holden | Props |
| Sound | Kirk Francis | Sound Mixer |
| Costume & Make-Up | Patrick Caulfield | Key Set Costumer |
| Camera | Joe Gajewski | Additional Grip |
| Production | Crista Birgy | First Assistant Accountant |
| Sound | Jackie Gleason | Musician |
| Production | Gail Rose | Post Production Accountant |
| Sound | Eric Flickinger | Sound Recordist |
| Visual Effects | Thomas J. Smith | Visual Effects Supervisor |
| Visual Effects | Eric Pender | CG Artist |
| Camera | George Kohut | Camera Operator |
| Crew | Michael Franck | Aerial Coordinator |
| Crew | Virginia Landis Albertson | Post Production Supervisor |
| Camera | David Norris | Aerial Director of Photography |
| Editing | Jim Passon | Color Timer |
| Crew | Joe Andaloro | Stand In |
| Crew | Kym Washington Longino | Stunt Double |
| Crew | Michelle Johnston | Choreographer |
| Crew | Linda Cohn | Thanks |
| Crew | Teresa Lang | Thanks |
| Crew | Michelle Sleger | Stand In |
| Crew | Troy Gilbert | Stunts |
| Crew | Linda Perlin | Stunts |
| Crew | Lance Gilbert | Stunts |
