When her boyfriend dumps Emily, a spontaneous woman in her 30s, she persuades her ultra-cautious mom to accompany her on a vacation to Ecuador. When these two very different women are trapped on this wild journey, their bond as mother and daughter is tested and strengthened while they attempt to navigate the jungle and escape.
| Directing | Jonathan Levine | Director |
| Writing | Katie Dippold | Writer |
| Writing | Amy Schumer | Screenplay |
| Writing | Kim Caramele | Screenplay |
| Camera | Florian Ballhaus | Director of Photography |
| Editing | Zene Baker | Editor |
| Art | Kevin Constant | Art Direction |
| Art | Chryss Hionis | Set Decoration |
| Sound | Tod A. Maitland | Sound Mixer |
| Production | Brent Anbe | Casting Associate |
| Costume & Make-Up | Phillip Howard | Costume Design |
| Costume & Make-Up | Dana Kay Hart | Costume Supervisor |
| Crew | Brian Machleit | Stunt Coordinator |
| Crew | Kevin Hannigan | Special Effects Coordinator |
| Production | Peter Chernin | Producer |
| Production | Paul Feig | Producer |
| Production | Jessie Henderson | Producer |
| Production | Michael Kruzan | Producer |
| Production | Donald J. Lee Jr. | Executive Producer |
| Production | Kim Caramele | Executive Producer |
| Production | Tonia Davis | Executive Producer |
| Production | Katie Dippold | Executive Producer |
| Production | Kevin Kane | Associate Producer |
| Production | Amy Schumer | Executive Producer |
| Production | Jenno Topping | Producer |
| Sound | Chris Bacon | Original Music Composer |
| Sound | Theodore Shapiro | Original Music Composer |
| Editing | Melissa Bretherton | Editor |
| Art | Mark Ricker | Production Design |
| Costume & Make-Up | Leesa Evans | Costume Design |
| Crew | Joan Kelley Bierman | Post Production Supervisor |
| Production | Kate Kelly | Production Supervisor |
| Art | Stella Vaccaro | Set Designer |
| Production | Julie Hannum | Location Manager |
| Art | Stephanie Spangler | Location Scout |
| Sound | Gabe Hilfer | Music Supervisor |
| Directing | Brenda Lopez | Script Supervisor |
| Costume & Make-Up | Julia Gadiana | Hairstylist |
| Costume & Make-Up | Nicki Ledermann | Makeup Department Head |
| Costume & Make-Up | Ralph Malani | Hairstylist |
| Costume & Make-Up | Pavy Olivarez | Key Hair Stylist |
| Costume & Make-Up | Laine Rykes | Key Makeup Artist |
| Costume & Make-Up | Joy Zapata | Hair Department Head |
| Directing | E. J. Foerster | Second Unit Director |
| Directing | Artist W. Robinson | First Assistant Director |
| Directing | Deanna Stadler | Second Assistant Director |
| Art | Robert A. Blackburn | Construction Coordinator |
| Art | Yann Denoual | Sculptor |
| Art | Jane Gulick | Property Master |
| Art | Gary Nakano | Graphic Designer |
| Art | William H. Phen Jr. | Construction Foreman |
| Art | Isaia Robins | Greensman |
| Art | Joelle-Lyn Sarte | Art Department Coordinator |
| Art | Ben Woodworth | Painter |
| Sound | Roberto Dominguez Alegria | Foley Mixer |
| Sound | Ignacio Arrojo | ADR Recordist |
| Sound | John T. Cucci | Foley Artist |
| Sound | Susan Dawes | Supervising Dialogue Editor |
| Sound | Joel Dougherty | Sound Re-Recording Mixer |
| Sound | Jay Fisher | ADR Mixer |
| Sound | Warren Hendriks | Supervising Sound Editor |
| Sound | David Lucarelli | ADR Recordist |
| Sound | Sean Massey | Supervising ADR Editor |
| Sound | Dan O'Connell | Foley Artist |
| Sound | Jason Oliver | ADR Mixer |
| Sound | Chris Terhune | Sound Designer |
| Sound | Jerry Yuen | Boom Operator |
| Visual Effects | Thomas F. Ford IV | Visual Effects Producer |
| Visual Effects | David Lingenfelser | Visual Effects Supervisor |
| Visual Effects | Rebecca Park | Visual Effects Producer |
| Crew | Jason Solberg | Visual Effects Editor |
| Crew | Rene Mousseux | Stunt Double |
| Crew | Ryan Gray | Stunt Double |
| Crew | Lisa Hoyle | Stunt Double |
| Crew | Damien Bray | Stunts |
| Crew | Bonnie Campanella | Utility Stunts |
| Crew | Craig H. Davidson | Stunts |
| Crew | Jess Lundgren | Stunts |
| Crew | Gary Price | Stunts |
| Crew | Meredith Richardson | Stunt Double |
| Crew | Mike Rufino | Stunts |
| Crew | Jason A. Triplett | Stunts |
| Crew | Todd Sells | Stunt Double |
| Camera | Rylan Akama | Assistant Camera |
| Camera | John Bonnin | Libra Head Technician |
| Camera | Don Chong | Dolly Grip |
| Lighting | Andy Day | Gaffer |
| Camera | Jason Ellson | Steadicam Operator |
| Camera | Don King | Camera Operator |
| Camera | Thomas Lappin | Camera Operator |
| Camera | Caleb Lucero | Second Assistant Camera |
| Camera | Vince Keala Lucero | Camera Operator |
| Camera | Duane Manwiller | Second Unit Director of Photography |
| Camera | Charlie Marroquin | Key Grip |
| Camera | Justina Mintz | Still Photographer |
| Lighting | Allen Mozo | Lighting Technician |
| Camera | David B. Nowell | Aerial Director of Photography |
| Camera | Ryan Rayner | First Assistant "A" Camera |
| Lighting | Marc 'Aina' Ribuca | Electrician |
| Camera | Andrew Sweeney | Dolly Grip |
| Lighting | Don Tomich | Rigging Gaffer |
| Editing | Eirinn Disbrow | Assistant Editor |
| Editing | Jamie Keeney | Assistant Editor |
| Editing | Ken O'Keefe | First Assistant Editor |
| Sound | Allegra De Souza | Music Editor |
| Production | Zoila Gomez | Production Coordinator |
| Crew | Cecile Meloni | In Memory Of |
| Art | Karen Teneyck | Graphic Designer |
| Crew | Rick Lovoy | Driver |
| Sound | Alejandro Uribe Holguín | ADR Recordist |
| Sound | Tom Brown | Music Arranger |
