When the renegade crew of Serenity agrees to hide a fugitive on their ship, they find themselves in an action-packed battle between the relentless military might of a totalitarian regime who will destroy anything – or anyone – to get the girl back and the bloodthirsty creatures who roam the uncharted areas of space. But... the greatest danger of all may be on their ship.
| Editing | Lisa Lassek | Editor |
| Production | Christopher Buchanan | Executive Producer |
| Directing | Joss Whedon | Director |
| Writing | Joss Whedon | Writer |
| Production | Alisa Tager | Executive Producer |
| Production | Barry Mendel | Producer |
| Production | David V. Lester | Executive Producer |
| Writing | Joss Whedon | Author |
| Art | Barry Chusid | Production Design |
| Costume & Make-Up | Ruth E. Carter | Costume Design |
| Art | Larry Dias | Set Decoration |
| Art | Jim Johnson | Set Decoration |
| Production | Amy McIntyre Britt | Casting |
| Costume & Make-Up | Camille Calvet | Makeup Department Head |
| Art | Daniel T. Dorrance | Art Direction |
| Production | Anya Colloff | Casting |
| Crew | Tim Rigby | Stunts |
| Costume & Make-Up | Tina Hoffman | Makeup Artist |
| Crew | Emile Edwin Smith | CG Supervisor |
| Visual Effects | Stephanie Pollard | Visual Effects Coordinator |
| Camera | Andrew Shulkind | Camera Operator |
| Camera | Sidney Ray Baldwin | Still Photographer |
| Costume & Make-Up | Scott Stoddard | Makeup Supervisor |
| Visual Effects | Collin Fowler | Visual Effects Coordinator |
| Lighting | Gary Tandrow | Chief Lighting Technician |
| Camera | Brad Boyer | Dolly Grip |
| Sound | Hector C. Gika | Sound Effects Editor |
| Sound | Eric Flickinger | Sound Recordist |
| Art | Robert A. Blackburn | Construction Coordinator |
| Visual Effects | James Turek | Visual Effects Coordinator |
| Visual Effects | John K. Stirber | Special Effects Supervisor |
| Sound | Tom Bellfort | Supervising Sound Editor |
| Costume & Make-Up | Jennifer Bell | Hairstylist |
| Costume & Make-Up | Vickie Mynes | Hairstylist |
| Visual Effects | Juliette Yager | Visual Effects Producer |
| Visual Effects | Lisa Goldberg | Visual Effects Producer |
| Camera | Peter N. Green | First Assistant Camera |
| Camera | Tony Olivieri | First Assistant Camera |
| Lighting | Minh Bahnsen | Rigging Grip |
| Crew | Paul Murphey | Video Assist Operator |
| Sound | Geoffrey G. Rubay | Supervising Sound Editor |
| Costume & Make-Up | Dana Kay Hart | Costume Supervisor |
| Crew | Josh Margolies | Visual Effects Editor |
| Sound | Kerry Ann Carmean | Sound Effects Editor |
| Sound | Karen Vassar Triest | Sound Effects Editor |
| Costume & Make-Up | Ryck Schmidt | Ager/Dyer |
| Editing | Bill Schultz | Digital Intermediate |
| Editing | Mo Henry | Negative Cutter |
| Production | Lauren Ross | Location Manager |
| Costume & Make-Up | Ron Pipes | Makeup Artist |
| Art | Gerald Sullivan | Assistant Art Director |
| Visual Effects | Chris Anderson | Visual Effects Coordinator |
| Visual Effects | Thomas Elder-Groebe | Visual Effects Coordinator |
| Visual Effects | Catherine Sudolcan | Visual Effects Producer |
| Visual Effects | Loni Peristere | Visual Effects Supervisor |
| Camera | Mark Emery Moore | Steadicam Operator |
| Visual Effects | Dan DeLeeuw | Visual Effects Supervisor |
| Camera | David B. Nowell | Aerial Director of Photography |
| Lighting | Jason Young | Electrician |
| Camera | Jerry C. Deats | Key Grip |
| Sound | Gwendolyn Yates Whittle | Dialogue Editor |
| Sound | Craig S. Jaeger | Foley Editor |
| Sound | Ron Bartlett | Sound Re-Recording Mixer |
| Editing | Dan Muscarella | Color Timer |
| Editing | Walter Volpatto | Digital Intermediate |
| Visual Effects | Susie Brubaker | Visual Effects Coordinator |
| Camera | Ryan Green | Camera Operator |
| Lighting | Chris Pavlu | Electrician |
| Sound | Gail Carroll-Coe | Boom Operator |
| Sound | John Cannon | First Assistant Sound Editor |
| Visual Effects | Fumi Mashimo | Animation Supervisor |
| Crew | Daniel Sudick | Special Effects Coordinator |
| Crew | Thomas Terry | Pilot |
| Sound | Ben Wilkins | Sound Effects Editor |
| Editing | Aidan Stanford | Color Timer |
| Crew | Bud Myrick | Digital Effects Supervisor |
| Visual Effects | Patrick D. Hurd | Visual Effects Coordinator |
| Visual Effects | Richard Malzahn | Visual Effects Supervisor |
| Camera | Raymond Stella | Second Unit Director of Photography |
| Camera | Sean Devine | Dolly Grip |
| Lighting | Justin Van Fleet | Rigging Grip |
| Art | Carla S. Nemec | Art Department Coordinator |
| Crew | Karl Herbst | Digital Effects Supervisor |
| Costume & Make-Up | Jordanna Fineberg | Assistant Costume Designer |
| Editing | Catherine Chase | First Assistant Editor |
| Lighting | John Davies | Electrician |
| Production | Sari Knight | Casting Associate |
| Visual Effects | Mary E. Manning | 3D Artist |
| Sound | Lou Kleinman | Dialogue Editor |
| Sound | John Roesch | Foley |
| Art | Lisa D. DiSanto | Art Department Coordinator |
| Lighting | George Lozano Jr. | Best Boy Electric |
| Lighting | Rex Anson Rhorer | Rigging Grip |
| Editing | John Nicolard | Digital Intermediate |
| Costume & Make-Up | Mary Kay Morse | Key Makeup Artist |
| Art | Brad Einhorn | Property Master |
| Visual Effects | Eric Withee | Visual Effects Coordinator |
| Sound | Michael Magill | Dialogue Editor |
| Sound | David A. Whittaker | Sound Effects Editor |
| Costume & Make-Up | Daniel Dirks | Key Costumer |
| Costume & Make-Up | Monica Haynes | Key Costumer |
| Costume & Make-Up | Sean Flanigan | Key Hair Stylist |
| Costume & Make-Up | Karen Iverson | Makeup Artist |
| Art | Kevin Kavanaugh | Assistant Art Director |
| Visual Effects | Steve Pimental | Visual Effects Coordinator |
| Crew | J.P. "Brendan" Bernardo | Visual Effects Editor |
| Visual Effects | Randy Goux | Visual Effects Supervisor |
| Directing | Jain Sekuler | Script Supervisor |
| Camera | Jack N. Green | Director of Photography |
| Costume & Make-Up | Christopher Allen Nelson | Key Makeup Artist |
| Costume & Make-Up | Garrett Immel | Key Makeup Artist |
| Costume & Make-Up | Margie Kaklamanos | Makeup Artist |
| Visual Effects | Rpin Suwannath | Pre-Visualization Supervisor |
| Visual Effects | Gary Nolin | Visual Effects Producer |
| Visual Effects | Les Hunter | Visual Effects Producer |
| Camera | Greg Karamov | Key Grip |
| Sound | Stephanie Flack | ADR Editor |
| Sound | Timothy P. Salmon | Boom Operator |
| Sound | Mark Smith | Sound Re-Recording Mixer |
| Editing | Scott Wesley Ross | Assistant Editor |
| Sound | David Newman | Original Music Composer |
| Art | Shawn Albro | Painter |
| Art | Jaremy Aiello | Sculptor |
| Sound | Art Rochester | Sound Mixer |
| Crew | Scott Burrows | Compositor |
| Crew | Eric Compton | Transportation Captain |
| Crew | Mary King | Craft Service |
| Art | Kelly Berry | Set Decoration Buyer |
| Sound | Andrew Bock | Assistant Sound Editor |
| Crew | Jack Carpenter | Driver |
| Crew | Louis Farah | Set Medic |
| Crew | Sage Asteak | Set Production Assistant |
| Crew | Virginia Landis Albertson | Post Production Supervisor |
| Lighting | James M. Cox | Rigging Gaffer |
| Sound | Gregory Jamrok | Orchestrator |
| Directing | Rich Sickler | First Assistant Director |
| Lighting | Jesse Jaraczewski | Best Boy Electric |
| Crew | Rob Harris | Unit Publicist |
| Crew | Mark Bialuski | Propmaker |
| Editing | James Dornoff | Editorial Production Assistant |
| Crew | Sophia Lansky | Dialect Coach |
| Production | Mary Sunshine | Production Accountant |
| Crew | Elizabeth Cameron | Stand In |
| Crew | Hank Amos | Stunts |
| Crew | Justin Ball | Systems Administrators & Support |
| Visual Effects | L. Patrick McCormack | Visual Effects |
| Sound | Jeff Carson | Music Editor |
| Art | Harald Belker | Production Illustrator |
| Crew | Regina McKee Redwing | Utility Stunts |
| Art | Chuck Eskridge | Standby Painter |
| Crew | Marcus Stokes | Sequence Supervisor |
| Crew | Donald R. Casella | Transportation Coordinator |
| Costume & Make-Up | Courtney J. Andersen | Set Dressing Artist |
| Camera | Steven A. Guerrero | Grip |
| Production | James Maull | Post Production Accountant |
| Production | David V. Lester | Unit Production Manager |
| Art | P. Scott Bailey | Leadman |
| Production | Christina Rollo | Production Coordinator |
| Sound | Norman Ludwin | Musician |
| Art | Pedro Barquin | Greensman |
| Art | Mick Cukurs | Set Designer |
| Crew | Ron Petruccione | Special Effects |
| Crew | Chad Stahelski | Stunt Coordinator |
| Art | Helen Wilson | Props |
| Directing | Maria Battle Campbell | Second Second Assistant Director |
| Art | James Lee Kroning | Assistant Property Master |
| Costume & Make-Up | Steve Constancio | Costumer |
| Art | Matt Codd | Concept Artist |
| Art | Julia Gombert | Textile Artist |
| Art | Chad Koch | Set Decorating Coordinator |
| Costume & Make-Up | Pilar Harlow | Contact Lens Technician |
| Art | Jarik Van Sluijs | Creative Director |
| Costume & Make-Up | Robert Miller | Costume Illustrator |
| Art | Trey Shaffer | Graphic Designer |
| Directing | Shaun O'Dell | Second Unit Director |
| Art | Joey Genitempo | Set Painter |
| Camera | Lynda Wu | Camera Loader |
| Production | Jill Rosenblatt | First Assistant Accountant |
| Editing | Greg Curry | Colorist |
| Editing | Anthony Harris | Digital Color Timer |
| Crew | Melissa Huerta | Intern |
| Sound | Scott Morgan | Foley Recordist |
| Editing | Patrick J. Barry | Assistant Editor |
| Sound | Rick Canelli | ADR Recordist |
| Camera | Jeffrey A. Johnson | Best Boy Grip |
| Sound | Alyson Dee Moore | Foley Artist |
| Crew | Karin Silvestri | Stunt Double |
| Visual Effects | Patti Gannon | Compositing Supervisor |
| Art | Gary Hebert | Title Designer |
| Production | Judy Cook | Extras Casting Assistant |
| Production | Blake Perkinson | Key Set Production Assistant |
| Crew | Roy Augenstein | Special Effects Technician |
| Crew | John Peter Bernardo | Visual Effects Editor |
| Production | Mark Asaro | Assistant Production Coordinator |
| Production | Sasha Adkinson | Extras Casting |
| Production | David Hickey | Payroll Accountant |
| Editing | John Daro | Digital Intermediate Editor |
| Sound | David Newman | Conductor |
| Visual Effects | Achint Bansal | Digital Compositor |
| Sound | Eric Gotthelf | ADR Mixer |
| Sound | Christopher Flick | Foley Supervisor |
| Camera | Mark Colicci | Assistant Camera |
| Camera | Heather Green | Second Assistant Camera |
| Visual Effects | Michael Lloyd | Matte Painter |
| Crew | Chris Palermo | Stunt Driver |
| Lighting | Robert Dudley | Key Rigging Grip |
| Crew | Richard Patterson | Digital Supervisor |
| Visual Effects | Jacqueline Cooper | VFX Artist |
| Sound | Mary Jo Lang | Foley Mixer |
| Production | Amanda Crockett | Art Department Production Assistant |
| Production | Carrie Levin | Casting Assistant |
| Production | Adam Balentine | Production Assistant |
| Production | Julia M. Sauder | Production Secretary |
| Production | Mollie Stallman | Key Production Assistant |
| Production | Jennifer Clark | Second Assistant Accountant |
| Crew | Henry Kingi Jr. | Stunts |
| Crew | Scott Cosgrove | Stunts |
| Crew | Sonja Munsterman | Stunts |
| Crew | J.J. Perry | Stunt Double |
| Crew | Steve Upton | Stunts |
| Crew | Ming Qiu | Stunts |
| Crew | David Hugghins | Stunts |
| Crew | John C. Meier | Stunts |
| Crew | Tyler Vogt | Stunts |
| Crew | Casey Pieretti | Stunts |
| Crew | Samuel Le | Stunts |
| Crew | David Leitch | Stunts |
| Crew | Yuri Hinson | Stunts |
| Crew | Clay Donahue Fontenot | Stunts |
| Crew | Jeff Imada | Stunts |
| Crew | Tim Trella | Stunts |
| Crew | Michael Hugghins | Stunts |
| Art | Ray Harvie | Storyboard Artist |
| Visual Effects | Adam 'Mojo' Lebowitz | Visual Effects |
| Visual Effects | David R. Morton | Matte Painter |
| Crew | Heidi Moneymaker | Stunts |
| Sound | David Williams | Dialogue Editor |
| Crew | Matt McColm | Stunts |
| Crew | Darrin Prescott | Stunts |
| Crew | Tommy J. Huff | Stunts |
