In a world ravaged by a virus infection, turning its victims into the Undead, Alice continues on her journey to find survivors and lead them to safety. Her deadly battle with the Umbrella Corporation reaches new heights, but Alice gets some unexpected help from an old friend. A new lead that promises a safe haven from the Undead takes them to Los Angeles, but when they arrive the city is overrun by thousands of Undead - and Alice and her comrades are about to step into a deadly trap.
| Directing | Paul W. S. Anderson | Director |
| Production | Paul W. S. Anderson | Producer |
| Production | Jeremy Bolt | Producer |
| Production | Don Carmody | Producer |
| Production | Bernd Eichinger | Producer |
| Production | Samuel Hadida | Producer |
| Production | Robert Kulzer | Producer |
| Editing | Niven Howie | Editor |
| Camera | Glen MacPherson | Director of Photography |
| Production | Hiroyuki Kobayashi | Producer |
| Production | Victor Hadida | Executive Producer |
| Production | Martin Moszkowicz | Executive Producer |
| Production | Robin D. Cook | Casting |
| Art | Arvinder Greywal | Production Design |
| Production | Suzanne Smith | Casting |
| Costume & Make-Up | Denise Cronenberg | Costume Design |
| Costume & Make-Up | Azalia Snail | Costume Design |
| Costume & Make-Up | Leslie A. Sebert | Makeup Department Head |
| Crew | Jo-Ann MacNeil | Makeup Effects |
| Costume & Make-Up | Vincent Sullivan | Hair Department Head |
| Costume & Make-Up | Carol Hartwick | Key Hair Stylist |
| Art | Brandt Gordon | Art Direction |
| Art | Carolyn A. Loucks | Set Decoration |
| Costume & Make-Up | Christina Smith | Makeup Artist |
| Directing | Nadia Guglieri | Script Supervisor |
| Directing | Dug Rotstein | Script Supervisor |
| Crew | Charles Taylor | Armorer |
| Crew | Al Vrkljan | Armorer |
| Costume & Make-Up | Arthur Rowsell | Assistant Costume Designer |
| Costume & Make-Up | Renee Fontana | Assistant Costume Designer |
| Art | Collingwood Brown | Art Department Coordinator |
| Production | Ronald Gilbert | Production Manager |
| Crew | Gregor Hutchison | Post Production Supervisor |
| Art | William Cheng | Set Designer |
| Art | Tucker Doherty | Set Designer |
| Art | Vladislav Fedorov | Set Designer |
| Art | Sorin Popescu | Set Designer |
| Art | James Blacker | Location Scout |
| Production | Jonathan Matthews | Location Manager |
| Art | Tracey Savein | Location Scout |
| Sound | Kevin Banks | Music Editor |
| Production | Melissa Girotti | Production Coordinator |
| Production | Brian Kobo | Production Coordinator |
| Crew | Dave Tommasini | Pilot |
| Camera | Jim Holmes | Best Boy Grip |
| Camera | Michael Carella | Camera Operator |
| Camera | Keith Murphy | Camera Operator |
| Camera | Roger Finlay | Camera Operator |
| Camera | Perry Hoffman | Camera Operator |
| Camera | Carly Brenner | Camera Trainee |
| Camera | Julia Seidman | Camera Trainee |
| Camera | Jeff Hicks | Camera Trainee |
| Camera | Dan Grease White | Camera Trainee |
| Camera | Vern Nobles | Aerial Director of Photography |
| Camera | David Franco | Second Unit Director of Photography |
| Camera | Igor Meglic | Second Unit Director of Photography |
| Camera | Ron Renzetti | Dolly Grip |
| Camera | John Colavecchia | First Assistant Camera |
| Camera | Mark Cyre | First Assistant Camera |
| Camera | Colin Akoon | First Assistant Camera |
| Camera | Marcel Janisse | First Assistant Camera |
| Camera | Brian White | First Assistant Camera |
| Lighting | Michael Galbraith | Gaffer |
| Lighting | Gary Deneault | Gaffer |
| Camera | Robert Johnson | Key Grip |
| Camera | Michael E. Matteson | Key Grip |
| Lighting | Tom Starnes | Rigging Gaffer |
| Lighting | Jim Krauter | Rigging Grip |
| Camera | Benjamin Smith | Second Assistant Camera |
| Camera | Michael Carr | Second Assistant Camera |
| Camera | Brian Cassar | Second Assistant Camera |
| Camera | Amanda Wojtaszek | Second Assistant Camera |
| Camera | Patrick King | Dolly Grip |
| Camera | Rafy | Still Photographer |
| Camera | Brent Robinson | Underwater Camera |
| Costume & Make-Up | Sondra Treilhard | Assistant Hairstylist |
| Costume & Make-Up | Burton J. LeBlanc | Assistant Makeup Artist |
| Costume & Make-Up | Cliona Furey | Hairstylist |
| Costume & Make-Up | Jo-Ann MacNeil | Key Makeup Artist |
| Costume & Make-Up | Sandra Wheatle | Makeup Artist |
| Costume & Make-Up | Graham Chivers | Prosthetic Makeup Artist |
| Costume & Make-Up | Jason Detheridge | Prosthetic Makeup Artist |
| Costume & Make-Up | Chris Devitt | Prosthetic Makeup Artist |
| Costume & Make-Up | Kyle Glencross | Prosthetic Makeup Artist |
| Costume & Make-Up | Iantha Goldberg | Prosthetic Makeup Artist |
| Costume & Make-Up | Shane Zander | Prosthetic Makeup Artist |
| Crew | Patrick Baxter | Makeup Effects |
| Crew | Kelly Kavanagh | Makeup Effects |
| Crew | Neil Morrill | Makeup Effects |
| Crew | Kelly O'Leary | Makeup Effects |
| Crew | Rocky Faulkner | Makeup Effects |
| Crew | Richard Redlefsen | Makeup Effects |
| Sound | Travis MacKay | ADR Mixer |
| Sound | Wade Barnett | ADR Recordist |
| Sound | Adam Horley | ADR Recordist |
| Sound | Andy Schlegel | ADR Recordist |
| Sound | Alan Zielonko | Boom Operator |
| Sound | Jill Purdy | Dialogue Editor |
| Sound | Steve F.B. Smith | Dolby Consultant |
| Sound | Rose Gregoris | First Assistant Sound Editor |
| Sound | Steve Baine | Foley Artist |
| Sound | Peter Persaud | Foley Recordist |
| Sound | Sean Paul Armstrong | Boom Operator |
| Sound | John J. Thomson | Sound |
| Sound | Coll Anderson | Sound Designer |
| Sound | Alex Bullick | Sound Effects Editor |
| Sound | Thomas Hayek | Sound Recordist |
| Sound | Andrew Stirk | Sound Re-Recording Mixer |
| Sound | Andrew Tay | Sound Re-Recording Mixer |
| Sound | Mark Zsifkovits | Sound Re-Recording Mixer |
| Sound | Stephen Barden | Supervising Sound Editor |
| Visual Effects | Hanung Lee | Animation |
| Visual Effects | Frankie Stellato | Animation |
| Visual Effects | Mehta Apul | Animation |
| Visual Effects | Peter Dydo | Animation |
| Visual Effects | Gavin Soares | Animation |
| Visual Effects | Emrah Gonulkirmaz | Animation |
| Visual Effects | Daniel Rhein | CG Artist |
| Visual Effects | Gabriel Tremblay-Beauvais | CG Artist |
| Crew | Craig Calvert | CG Supervisor |
| Crew | Dominic Remane | CG Supervisor |
| Crew | Louis Katz | CG Supervisor |
| Visual Effects | Robert Greb | Compositing Supervisor |
| Crew | Ovidiu Cinazan | Compositor |
| Crew | Kaitlyn Lovatt | Compositor |
| Crew | Prasenjit Mukherjee | Compositor |
| Crew | Chris Ryan | Compositor |
| Crew | Kamal Kumar Tiwari | Compositor |
| Crew | Mrityunjay Singh | Compositor |
| Art | Mahapatro Kalpana | Concept Artist |
| Art | Mark Fordham | Concept Artist |
| Crew | Sébastien Moreau | Digital Effects Supervisor |
| Lighting | Engin Arslan | Lighting Artist |
| Lighting | Allan Henderson | Lighting Artist |
| Lighting | Brian Dignadice | Lighting Artist |
| Visual Effects | Mathew Borrett | Matte Painter |
| Visual Effects | Ken McCuen | Matte Painter |
| Visual Effects | Ravindra Tamhankar | Matte Painter |
| Visual Effects | Peter Toufidis | Matte Painter |
| Visual Effects | Milan Schere | Matte Painter |
| Visual Effects | Tracey McLean | Matte Painter |
| Visual Effects | Stéphan Brisson | Matte Painter |
| Visual Effects | Marilyne Fleury | Matte Painter |
| Visual Effects | Éric Hamel | Matte Painter |
| Visual Effects | Ludovic Iochem | Matte Painter |
| Visual Effects | Moika Sabourin | Matte Painter |
| Visual Effects | Frederic St-Arnaud | Matte Painter |
| Visual Effects | Robin Tremblay | Matte Painter |
| Visual Effects | Joell Xin Zhow | Matte Painter |
| Visual Effects | Kevin Labanowich | Senior Animator |
| Crew | Mathieu Raynault | Visual Effects Art Director |
| Visual Effects | Becca Donohoe | Visual Effects Coordinator |
| Visual Effects | Leann Harvey | Visual Effects Coordinator |
| Visual Effects | Benjamin Mossman | Visual Effects Coordinator |
| Visual Effects | Julien Tremblay | Visual Effects Coordinator |
| Visual Effects | Sarah Barber | Visual Effects Coordinator |
| Visual Effects | Josiane O'Rourke | Visual Effects Coordinator |
| Crew | Mike Barber | Visual Effects Editor |
| Crew | Florian Vera | Visual Effects Editor |
| Visual Effects | Eric J. Robertson | Visual Effects Producer |
| Visual Effects | Tavia Charlton | Visual Effects Producer |
| Visual Effects | Justin Smith | Visual Effects Production Assistant |
| Visual Effects | Geneviève Morin | Visual Effects Production Assistant |
| Visual Effects | Gabriel Roy | Visual Effects Production Assistant |
| Visual Effects | Lee Ann Simard | Visual Effects Production Assistant |
| Visual Effects | Mike Borrett | Visual Effects Production Manager |
| Visual Effects | Eric Robinson | Visual Effects Production Manager |
| Visual Effects | Dennis Berardi | Visual Effects Supervisor |
| Visual Effects | Ian Hunter | Visual Effects Supervisor |
| Visual Effects | Wojciech Zielinski | Visual Effects Supervisor |
| Visual Effects | Tom Turnbull | Visual Effects Supervisor |
| Editing | Lara Johnston | Assistant Editor |
| Editing | Harry Muller | Color Timer |
| Editing | Chris Wallace | Digital Intermediate Colorist |
| Editing | Motassem Younes | Digital Intermediate Editor |
| Editing | Peter Armstrong | Digital Intermediate Producer |
| Editing | Lee Hughes | Digital Intermediate |
| Editing | Ben Howdeshell | First Assistant Editor |
| Editing | Dawn M. Stoliar | First Assistant Editor |
| Sound | Tom Hajdu | Original Music Composer |
| Sound | Andy Milburn | Original Music Composer |
| Crew | Angelica Lisk-Hann | Stunts |
| Crew | Stephannie Hawkins | Stunts |
| Crew | Mary Ann Stevens | Stunts |
| Crew | Karen Leach | Stunts |
| Crew | Joanne Leach | Stunts |
| Crew | Vanessa King | Stunts |
| Crew | Liise Keeling | Stunts |
| Crew | Taryn Ash | Stunts |
| Crew | Rick Forsayeth | Stunt Coordinator |
| Writing | Paul W. S. Anderson | Writer |
| Sound | tomandandy | Music |
| Crew | Dana Howes | Transportation Coordinator |
