Tom Grant has found a rich gold vein and Bart Eaton is after it. Tom's sister Mary heads for the gold fields and Eaton and his men follow. Eaton teams up with Ace Daggett who plans to doublecross him and get the gold for himself. They frame Tom for murder and then try to get him to sign over his claim. The famous scout Tex Houston is on hand, escaping the attempts on his life, saving Mary from various perils, and trying to bring in the real killer and clear Tom.
A white woman is kidnapped from her home by Apache Indians. Traded to the Mojave Indians, she lives as a squaw for 11 years until she is found by her husband. Unfit for society he keeps her in a shack in the desert. Her solitary existence is transformed with the arrival of a Mexican. He befriends her, reignites her self-worth and increases her confidence. He re-introduces her to her husband and leaves. As he is leaving town he is ambushed by her husbands men and there is a gun-battle. Who lives and who dies?
Ken Williams is determined to discover the identity of the mysterious Rattler, who preys upon railroads and transportation companies like that owned by Jane Corwin. The Rattler is especially difficult to catch because of his skill at disguising himself as other people.
It is the old west and the Dillon clan are making life miserable for a small Western town. Sweetheart Nell (Christine McIntyre) and her dashing but dimwitted boyfriend Elmer (Jock Mahoney) rushes off to find help. Meanwhile, cavalrymen the Stooges are making life miserable for superior, Sergeant Mullins (Dick Wessel). Mullins tries to whip the boys into shape, but his plan backfire and has a run-in with his superior, Captain Daley (Emil Sitka). Daley informs Mullins about the Dillion clan's evildoings, and needs some men to run them out of town. Mullins does not miss a beat, and volunteers the unsuspecting Stooges.
Art Louden, foreman of the Bar H Ranch, is contemptuous of the masculine city flappers and effeminate city sheiks who are vacationing on the ranch, and when reproached by the owner, Bill Hayes, for discourtesy to a guest, Art complains that there are no "she-women" left. Seeing a newspaper photo of Iris Millard, he is attracted by her apparent innocence; then she arrives with her father, and Art is disillusioned to find her as snobbish and as jazzily dressed as the others. His disdain, however, causes Iris to play up to his ideas.
Fifteen years after their father was gunned down in cold blood, Cashius and Winston Hurley return to their hometown to avenge his death. Joining forces with their cousin Bugsy, the two gun-slinging brothers hunt down everyone involved in their father's murder. As the bullets fly and the death toll rises, the three young cowboys find themselves fugitives from the law, running for their lives and fighting for their revenge.
Hoppy goes undercover as a gambler from the East when Bar 20 cattle are stolen by unknown rustlers. Brennan/Talbot are twin brothers (one a casino owner, the other a rancher) and Hoppy believes they provide alibis for each other while one is out committing crimes. Hoppy gets a job in the casino to learn more but is exposed when a gambling gunslinger notices him.
Big Hearted Jim, the sheriff, loves the tomboyish Nugget Nell ( Dorothy Gish ), who runs a hash house in the mining country, but although she has romantic feelings, they are not aroused by Jim. Nell agrees to an old miner friend's request to care for his "child," Nell is shocked to meet the six-foot girl, but she cares for her just the same. Nell falls in love with the City Chap, out West to look after his mining property, but he barely notices her, having become intrigued by the Ingenue, whom he met on the stagecoach. The jealous Nell steals stylish clothes to allure him, but she has trouble walking in French high-heels.
"Chuck" Peters, a gambler, is in love with Nell Braley, the daughter of the town saloon keeper. Nell, however, loves Bob Coleman, a cattleman. The express messenger is held up in the woods and the bandit escapes, leaving a snake hatband as a clue. Coleman inherits money, and as he is riding to the next town, finds the hatband and buckles it around his sombrero.
The Goddess, the prettiest and best-natured girl that ever graced that little mining town, meets the tenderfoot prospector and leaves him another worshiper of her. His chances, however, are slim for Blue-grass Pete has won her affections, he having at an opportune moment saved her from the fangs of a snake which was about to attack her. Pete's affections turn to the Goddess's sister, while Pete's friends plot to rob.
Rambler Shinji arrives in town armed with nothing but a guitar. With assistance from an old gun-for-hire friend, he sets about to stop the mob from turning an honest ranch into a gambling resort.
The Government sends Dean, Baxter, and Gordon to investigate a series of train holdups. Travis is behind the robberies and they are soon on his trail. When things get hot, Travis has a plan of double-crossing his own men that will enable him to keep not only his gold but also the money it is insured for.
Durango, aka Steve Rollins rides into town with saddle pal Smiley Burnette. The boys go to the rescue of pretty Kathleen Case, who is being victimized by greedy relatives.
Carter Brace is out to murder Belden. Collins who was sent to bring in the border gang led by Brace, saves Belden's life in San Francisco. When they all reach the border, Brace tries again.