Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
| Directing | Terry Gilliam | Director |
| Production | Patrick Cassavetti | Producer |
| Production | Laila Nabulsi | Producer |
| Production | Stephen Nemeth | Producer |
| Camera | Nicola Pecorini | Director of Photography |
| Editing | Lesley Walker | Editor |
| Production | Margery Simkin | Casting |
| Art | Alex McDowell | Production Design |
| Art | Chris Gorak | Art Direction |
| Art | Nancy Haigh | Set Decoration |
| Costume & Make-Up | Julie Weiss | Costume Design |
| Writing | Terry Gilliam | Screenplay |
| Production | Elliot Lewis Rosenblatt | Co-Producer |
| Art | Ronald Day | Painter |
| Art | Lynn Christopher | Set Designer |
| Crew | JoAnn Fregalette Jansen | Choreographer |
| Art | Mark Weissenfluh | Leadman |
| Art | Glen Hanz | Sculptor |
| Art | Mark Blumenthal | Standby Painter |
| Camera | Frank Perl | Camera Operator |
| Writing | Tony Grisoni | Screenplay |
| Writing | Tod Davies | Screenplay |
| Writing | Alex Cox | Screenplay |
| Production | Harold Bronson | Executive Producer |
| Production | Richard Foos | Executive Producer |
| Production | John Jergens | Associate Producer |
| Sound | Ray Cooper | Original Music Composer |
| Art | Dianne Chadwick | Art Department Assistant |
| Art | Andrea Carter | Art Department Coordinator |
| Art | Dan Pemberton | Construction Coordinator |
| Art | Tom Lifsey | Construction Foreman |
| Art | Frank McEldowney | Greensman |
| Art | Tani Kunitake | Production Illustrator |
| Camera | Łukasz Bielan | First Assistant Camera |
| Camera | Nicola Pecorini | Steadicam Operator |
| Camera | Peter Mountain | Still Photographer |
| Costume & Make-Up | Kimberly Adams | Assistant Costume Designer |
| Costume & Make-Up | Eden Clark Coblenz | Costume Supervisor |
| Costume & Make-Up | Bridget Cook | Hairstylist |
| Costume & Make-Up | Olga Ishkhanova | Seamstress |
| Costume & Make-Up | Linda S. Cormany | Set Costumer |
| Costume & Make-Up | Bill Fletcher | Wigmaker |
| Crew | Gary Gingold | Craft Service |
| Crew | Pedro Amaya | Driver |
| Crew | Rob Bottin | Makeup Effects |
| Crew | Randy Benjamin | Picture Car Coordinator |
| Crew | Roanne Moore | Post Production Assistant |
| Crew | Michael Solinger | Post Production Supervisor |
| Crew | Earl F. Betts | Propmaker |
| Crew | Maureen Kropf | Scenic Artist |
| Crew | Gloria M. Fujita | Set Medic |
| Crew | Jimmy Bennett | Set Production Assistant |
| Crew | Steve Galich | Special Effects Coordinator |
| Crew | Matt Langenbach | Stand In |
| Crew | Noon Orsatti | Stunt Coordinator |
| Crew | Kelly Joe Dugan | Stunts |
| Crew | Pat Stubbs | Transportation Co-Captain |
| Crew | James Lowder | Transportation Coordinator |
| Production | Mark Indig | Unit Production Manager |
| Crew | Michael Singer | Unit Publicist |
| Crew | Ian Kelly | Video Assist Operator |
| Directing | Karon May | Script Supervisor |
| Editing | David Rees | Color Timer |
| Lighting | James Babineaux | Best Boy Electric |
| Lighting | Reynaldo Barrera | Electrician |
| Lighting | Christopher Lyons | Gaffer |
| Production | Molly Allen | Location Manager |
| Production | Pearl A. Lucero | Production Coordinator |
| Production | Deborah Ricketts | Researcher |
| Sound | Randy Smith | Boom Operator |
| Sound | Jay Meagher | Production Sound Mixer |
| Sound | Dominic Lester | Sound Re-Recording Mixer |
| Sound | Peter Pennell | Supervising Sound Editor |
| Visual Effects | Ray Svedin | Special Effects Supervisor |
| Visual Effects | Michael Cooper | Visual Effects Coordinator |
| Visual Effects | Kent Houston | Visual Effects Supervisor |
| Sound | Kevin Lane | Music Editor |
| Art | Paige Augustine | Set Dresser |
| Camera | Peter Chrimes | Key Grip |
| Costume & Make-Up | Cheryl Ann Nick | Key Makeup Artist |
| Sound | Martin Cantwell | Assistant Sound Editor |
| Camera | Lila Byall | Camera Loader |
| Camera | Carlos M. Gallardo | Dolly Grip |
| Camera | Michael Mick Armstrong | Grip |
| Costume & Make-Up | Rebeka L. Roberts | Ager/Dyer |
| Costume & Make-Up | John Linsmeier | Key Costumer |
| Costume & Make-Up | Lisa Rocco | Makeup Artist |
| Directing | Philip A. Patterson | First Assistant Director |
| Directing | Christina Fong | Second Assistant Director |
| Production | Nancy Restuccia | Assistant Production Coordinator |
| Production | Carmen Cuba | Casting Assistant |
| Sound | Joe Gallagher | ADR Editor |
| Sound | Stephen Bridgewater | ADR Supervisor |
| Sound | Bob Risk | Foley Editor |
| Sound | Caroline Dale | Musician |
| Sound | David Acord | Utility Sound |
| Costume & Make-Up | Bryan Birge | Costumer |
| Directing | Seth Edelstein | Second Second Assistant Director |
| Directing | Bruce Logan | Second Unit Director |
| Art | Martin Charles | Graphic Designer |
| Art | P. Scott Bailey | Swing |
| Sound | J.R. Westen | ADR Mixer |
| Crew | Joe Barden | Special Effects Assistant |
| Crew | Jimmy Ortega | Stunt Double |
| Camera | Vidal Cohen | Best Boy Grip |
| Camera | Sonja Rom | Camera Production Assistant |
| Camera | Steve Itano | First Assistant "A" Camera |
| Camera | Warren Feldman | Second Assistant Camera |
| Costume & Make-Up | Amy Gilliam | Wardrobe Assistant |
| Editing | Jeremy Hume | Assistant Editor |
| Production | R. Scott Poole | Assistant Location Manager |
| Production | Serena Baker | Location Assistant |
| Production | Alisa Moeller | Assistant Production Coordinator |
| Crew | Jose Gonzales | Catering |
| Production | Susan Giordano | First Assistant Accountant |
| Crew | Sav Akyüz | Intern |
| Production | Kristen Felan | Payroll Accountant |
| Production | Keli Craig | Production Assistant |
| Production | Jenni Wieland | Second Assistant Accountant |
| Sound | Paul Carr | ADR Recordist |
| Sound | Alan Paley | Dialogue Editor |
| Art | Will Blount | Property Master |
| Crew | Ernie F. Orsatti | Stunts |
| Writing | Hunter S. Thompson | Novel |
